Objective To develop the Perceived Nurse-Patient Relationship Scale and test its reliability and validity.Methods Based on literature review,qualitative interviews,and expert consultation,a preliminary draft of the Perceived Nurse-Patient Relationship Scale was developed.From June to August 2020,convenience sampling was used to select 2 578 clinical nurses from 49 Class Ⅲ hospitals in Hubei Province as research subjects,and reliability and validity testing were conducted on the scale.Results Exploratory factor analysis extracted three common factors,including 18 items,with a cumulative variance contribution rate of 74.702%.Confirmatory factor analysis showed that the model fitted well.The scale-content validity index was 0.983,and the item-content validity index was 0.900 to 1.000.The Cronbach's α coefficient of the scale was 0.955,with a split-half reliability of 0.883.Conclusions The Perceived Nurse-Patient Relationship Scale has good reliability and validity,and can be used to measure the nurse-patient relationship perceived by nurses.