摘要
目的 检索并评价帕金森病患者便秘评估和管理的最佳证据,为临床工作者有效管理帕金森病患者便秘提供循证依据.方法 计算机检索UpToDate、BMJ最佳实践、Cochrane Library、澳大利亚乔安娜布里格斯研究所循证卫生保健中心数据库、CINAHL、Medline、PubMed、英国国家卫生与服务优化研究所、循证医学数据库、Ovid医学全文期刊数据库、中国知网、万方数据库、中国生物医学数据库、中国指南网、世界卫生组织官网及各国帕金森病协会、神经病协会、消化病协会关于帕金森患者便秘的相关文献,检索时限为2018年12月—2023年12月.对文献进行方法学质量评价后,对相关证据进行提取、汇总.结果 共纳入12篇文献,其中临床决策1篇,指南4篇,系统评价3篇,专家共识4篇,最终从筛查和评估、非药物干预、药物干预、健康教育4个方面汇总了 15条证据.结论 本研究从多种维度总结了关于帕金森病患者便秘评估与管理的最佳证据,为临床工作者提供了循证依据.
Abstract
Objective To retrieve and evaluate the best evidence on the assessment and management of constipation in Parkinson's disease(PD)patients and provide clinical practitioners with evidence-based guidelines for effectively managing constipation in this patient group.Methods A comprehensive literature search was conducted in databases including UpToDate,BMJ Best Practice,Cochrane Library,Joanna Briggs Institute Evidence-Based Healthcare Center,CINAHL,Medline,PubMed,National Institute for Health and Care Excellence,Evidence-Based Medicine database,Ovid,China National Knowledge Infrastructure,Wanfang Database,SinoMed,Chinese Guidelines Network,World Health Organization website,and various national PD,neurology,and gastroenterology associations'websites.The search covered literature from December 2018 to December 2023.The methodological quality of the retrieved literature was assessed,and relevant evidence was extracted and summarized.Results A total of 12 articles were included:one clinical decision-making article,four clinical guidelines,three systematic reviews,and four expert consensus.Fifteen pieces of evidence were summarized from four aspects:screening and assessment,non-pharmacological interventions,pharmacological interventions,and health education.Conclusions This study summarized the best evidence for the assessment and management of constipation in PD patients from various dimensions and provided evidence-based guidelines for clinical practitioners.
基金项目
首都卫生发展科研专项(首发2022-4-20114)
首都医科大学宣武医院2024年度护理专项课题(HLQN2024008)
维普
万方数据