首页|急性脑梗死中风证型与血清胰岛素样生长因子-1和其结合蛋白-3水平的关系

急性脑梗死中风证型与血清胰岛素样生长因子-1和其结合蛋白-3水平的关系

Research on the relationship between traditional Chinese medicine's syndrome and serum level of IGF-1 and IGFBP-3 in patients with acute cerebral infarction

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Objective To study the relationship between traditional Chinese medicine (TCM) syndrome and serum level of IGF-1 and IGFBP-3 in patients with acute cerebral infarction (ACI).Methods 75 patients of ACI were divided into two groups by TCM` s syndrome differentiation: apolexy involving the channels (AIC) and apolexy involving the viscera (AIV).Serum level of IGF-1 and IGFBP-3 was detected by ELISA di-antibody clipping technique (DACT) and was compared with that of 30 normal controls.Results Serum level of IGF-1 and IGFBP-3 in AIC group and AIV group were significantly different from control groups;and differences between AIC group and AIV group were statistically significant.Serum level of IGF-1 and IGFBP-3 in all syndromes of AIC group and AIV group were remarkably lower than control group.Among them,syndrome of Yin-deficiency of liver and kidney and sthenia liver-yang and syndrome of blood stasis due to Qi deficiency had lower serum level of IGF-1 and IGFBP-3 than syndrome of empty and obstruction of channel.So did collapse syndrome and syndrome of mental disorder due to phlegm-fire to syndrome of wind-fire evil lucid orifices and block Yin syndrome.Conclusion There are to some extent correlation with TCM's Syndrome and serum level of IGF-1 and IGFBP-3 in patients with ACI. Serum level of IGF-1 and IGFBP-3 might be microcosmic referent markers of the damage of Qi and Yin by TCM` s syndrome differentiation.

acute cerebral infarctionTCM's syndromeIGF-1IGFBP-3

俞征宙、刘楠、陈玉玲、林信富

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Second People's Hospital of Fujian Traditional Chinese Medicine,Fujian 350003,China

Union Hospital of Fujian Medical University

acute cerebral infarction TCM's syndrome IGF-1 IGFBP-3

sustentation fund from Fujian province Educational Committee

JA02207

2002

中国组织工程研究
中国康复医学会,《中国组织工程研究与临床康复》杂志社

中国组织工程研究

CSTPCD
影响因子:1.387
ISSN:2095-4344
年,卷(期):2002.6(23)
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