首页|新型混编支架的制备与径向支撑力学行为

新型混编支架的制备与径向支撑力学行为

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背景:编织支架因良好的柔顺性被广泛应用于狭窄动脉的治疗,但在提供足够的径向支撑性能方面存在明显局限.目的:针对单一材料制成的编织支架存在径向支撑力不足的问题,采用不同力学参数的生物可降解材料混合编织支架,探究影响混编支架径向力学性能的影响因素.方法:在镁合金支架中引入铁合金纱线,采用有限元分析法对不同编织参数的混编支架进行参数化分析,通过与0.18 mm直径镁合金纱线制备的普通支架进行对比,评估其径向支撑力、径向回弹率和扩张不均匀性.结果与结论:①当铁合金纱线直径为0.18 mm和0.14 mm时,随着铁合金纱线数量的增多,混编支架的径向支撑力增加;此时,尽管直径0.14 mm铁合金纱线提供的径向支撑力小于同数量的0.18 mm铁合金纱线,但增加细铁合金纱线的数量可以达到与较粗铁合金纱线混编支架相媲美的径向支撑力.当铁合金纱丝直径为0.10 mm时,随着铁合金纱线数量的增加,混编支架的径向支撑力降低.②增大编织角度,混编支架的径向支撑力降低,但其径向回弹率和狗骨率得到了改善.通过降低编织角可以改善小直径铁合金纱线造成的支架径向支撑力不足.③结果显示,在镁合金支架中引入铁合金纱线,可以实现在不增加纱线直径的情况下精确地调整支架的径向力学性能,这不仅克服了单一材料支架的局限性,也为多材料支架的设计提供了新思路.
Preparation and radial support mechanical behavior of new mixed braided stents
BACKGROUND:Braided stents are widely used for treating stenotic arteries due to their good flexibility,but they have significant limitations in providing adequate radial support.OBJECTIVE:In response to the lack of radial support of braided stents made of a single material,a mixed braided stent using biodegradable materials with different mechanical parameters was developed to explore the influencing factors affecting the radial mechanical properties of the mixed braided stent.METHODS:Fe-alloy yarn was introduced into the Mg-alloy stents,and the stents with various braiding parameters were analyzed using finite element analysis.The radial support,radial recoil and expansion non-uniformity of the mixed braided stents were evaluated by comparing with ordinary 0.18 mm Mg-alloy stents prepared by yarn.RESULTS AND CONCLUSION:(1)When the Fe-alloy yarn diameters were 0.18 mm and 0.14 mm,the radial support force of the stent increased continuously with the introduction of more and more Fe-alloy yarns.Although the radial support provided was less by the 0.14 mm Fe-alloy yarns than by the same number of 0.18 mm Fe-alloy mixed braided stents,an increase in the number of Fe-alloy yarns resulted in a radial support comparable to that of the thicker Fe-alloy yarns.When the Fe-alloy yarn diameter was 0.10 mm,the radial support of the stents decreased with the increase in the number of Fe-alloy yarns.(2)When the braiding angle was increased,the radial support force of the stents was reduced,but the radial recoil and expansion non-uniformity were improved.By adjusting the braided angle,the lack of radial support force caused by small diameter Fe-alloy yarns could be improved.(3)It is concluded that this method can improve the radial mechanical properties of the stent without increasing the yarn diameter.This not only overcomes the limitation of single-material stents,but also provides a new idea for the design of multi-material stents.

braided stentsbioresorbable materialsmagnesium-alloysiron-alloysstent structureradial support propertiesdog-bone ratefinite element analysis

薛广明、木合塔尔·克力木、李洪

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新疆大学机械工程学院,新疆维吾尔自治区乌鲁木齐市 830047

编织支架 生物可降解材料 镁合金 铁合金 支架结构 径向支撑性能 狗骨率 有限元分析

2025

中国组织工程研究
中国康复医学会,《中国组织工程研究与临床康复》杂志社

中国组织工程研究

北大核心
影响因子:1.387
ISSN:2095-4344
年,卷(期):2025.29(16)