A multicenter study of the prevalence of oral lichen planus among residents in Chengdu City and the influencing factors
Objective To investigate the baseline characteristics,disease conditions and symptoms,clinical manifestations and dietary habits of patients with oral lichen planus(OLP)treated in hospitals from Chengdu City,and to analyze the influencing factors.Methods From January 2020 to December 2022,533 patients diagnosed as OLP in the People's Hospital of Jianyang City,Medical Center Hospital of Qionglai City and Chengdu Pidu District Hospital of TCM were enrolled in observation group.A total of 100 healthy volunteers during the same period were enrolled in the control group.Baseline characteristics,disease conditions and symptoms,clinical manifestations and dietary habits of OLP patients were analyzed.Independent risk factors for OLP were recognized by binary logistic regression analysis.Results Redness or congestion lesions(62.85％)were the most common manifestation of OLP,followed by oral mucosal lesions(20.08％),asymptomatic form(7.88％),rough surface(6.38％),and ulcers or erosion(2.81％).The buccal mucosa(59.29％)was the mainly affected site by OLP.Atrophic lichen planus(56.47％)was the most common variate of OLP in our cohort.Relevant factors for OLP were investigated,including the sex,age,marriage,medical history,dietary habits,oral hygiene and mental factors.There were no significant differences in the hospital visits,marriage,medical history,smoking,drinking,tea drinking,drug allergies,and tooth brushing frequency between observation group and control group(P＞0.05).Significant differences were detected in the sex,age,spicy diet,hot diet,hard diet and mental factors between groups(P＜0.05).Logistic regression analysis results showed that female gender,30-60 years of age,spicy diet,hot diet,hard diet and mental factors were independent risk factors for OLP(all P＜0.05).Conclusion Redness or congestion lesions are the most common manifestation of OLP patients in Chengdu City,with the most affected site of buccal mucosa and most common variate of atrophic lichen planus.Female gender,30-60 years of age,spicy diet,hot diet,hard diet and mental factors were independent risk factors for OLP in Chengdu City.Recognizing and managing risk factors for OLP prevent the aggravation and relapse.
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