Clinicopathological analysis of salivary gland tumors in Tibet Plateau
Objective To analyze the incidence of salivary gland tumors in the Department of Stomatology,Tibet Autonomous Region People's Hospital in the past 10 years,so as to preliminarily understand the incidence trend of salivary gland tumors In high-altitude regions.Methods The clinical data of 160 patients with salivary gland tumors admitted to Tibet Autonomous Region People's Hospital from 2013 to 2023 were retrospectively analyzed,including gender,age,location of tumors,pathological types,surgical methods and postoperative neurological function.Results Among the 160 patients,the age of onset ranged from 2 to 88 years,with an average age of 42.4 years.The peak period of tumor incidence was 20~60 years old.The ratio of male to female was 0.93∶1,and the ratio of benign to malignant ratio was 7∶1,the ratio of male to female for malignant tumors(2.33∶1)was significantly higher than that for benign tumors(0.79∶1)(P<0.05).The most common benign and malignant tumors were pleomorphic adenoma(101 cases)and nonspecific adenocarcinoma(5 cases).Parotid gland was the most common site of salivary gland tumor,accounting for 63.1%(101/160),followed by submandibular gland(20%)and palatal minor salivary gland(16.3%).The mean maximum diameter of 160 salivary gland tumors was 4.17 cm.The operative time and probability of facial nerve injury after partial parotidectomy were significantly lower than those after superficial parotidectomy(P<0.05).Conclusion The number of patients with salivary gland tumors in the Tibet Autonomous Region has increased year by year,mainly from the surrounding areas of Lhasa.The incidence of salivary gland malignancy is significantly higher in males than in females.Pleomorphic adenoma and non-specific adenocarcinoma are the most common benign and malignant salivary gland tumors.Compared with superficial parotidectomy,partial parotidectomy can significantly shorten the operative time and reduce the risk of facial nerve injury in patients with benign parotid tumors.