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新生儿高胆红素血症不良事件风险分析及其预测模型的建立

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针对新生儿高胆红素血症(Neonatal Hyperbilirubinemia,NHB)不良事件风险难以预测问题建立列线图模型进行预测。首先收集可能影响NHB不良事件发生的相关因素,根据有无脑损伤、心肌损害将患儿分组,行多因素分析,建立列线图模型并进行内部验证。结果表明 183例NHB患儿中共有 34例(17。99%)出现不良事件。出生孕周、喂养方式、产次、TBIL、IBIL、血乳酸为NHB患儿不良事件的独立性影响因素。采用Bootstrap法重复抽样、校准曲线结果显示及ROC结果提示列线图模型预测NHB患儿不良事件风险具有较高准确度与区分度。
Risk analysis of adverse events in neonatal hyperbilirubinemia and establishment of a predictive model
A line graph model was developed to predict the risk of adverse events in neonatal hyperbilirubinemia(NHB),which is difficult to predict.Firstly,we collected relevant factors that might influence the occurrence of NHB adverse events,grouped children according to the presence or absence of brain injury and myocardial damage,performed multifactorial analysis,established a line graph model and performed internal validation.The results showed that a total of 34(17.99%)of 183 children with NHB had adverse events.Week of gestation at birth,feeding method,number of deliveries,TBIL,IBIL,and blood lactate were independent influencing factors for adverse events in children with NHB.Repeated sampling using Bootstrap method,calibration curve result display and ROC results suggest that the column line graph model predicts the risk of adverse events in children with NHB with high accuracy and discriminat.

neonatal hyperbilirubinemiaAdverse eventsColumn chart modelRisk prediction

邓以婷娜、徐玲、颜凯、吴玉萍

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成都市双流区妇幼保健院,新生儿科,四川成都 610200

新生儿高胆红素血症 不良事件 列线图模型 风险预测

2024

现代科学仪器
中国分析测试协会

现代科学仪器

CSTPCD
影响因子:0.329
ISSN:1003-8892
年,卷(期):2024.41(1)
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