Network Meta-analysis of Chinese Patent Medicine containing Hawthorn in Treatment of Atherosclerosis
Purpose:To systematically evaluate the efficacy and safety of Chinese patent medicines containing hawthorn in the treatment of atherosclerosis.Method:Databases were searched for RCTs of Chinese patent medicines for atherosclerosis.Screening was performed by inclusion and exclusion criteria,and network meta-analysis was performed for outcomes.Results:A total of 40 articles were included,involving 6 Chinese patent medicines containing hawthorn,and the results showed that Yin Dan Xin Nao Tong Capsules combined with statins reduced TC and TG and increased HDL-C better.He Dan Tablets combined with statins reduce LDL-C and hs-CRP better.Pu Shen Capsules combined with statins improve clinical efficacy better.The experimental group had fewer adverse effects than the control group.Conclusion:Statins combined with hawthorn-containing Chinese patent medicines can improve clinical efficacy.However,based on the shortcomings of this study,the results of this ranking should be carefully referenced.However,more multicenter,large-sample,high-quality RCTs need to be supplemented.
Chinese patent medicineatherosclerosisHawthornNetwork Meta-analysis
万方数据
维普
