PS modified administration and flow CPAP ventilator for the treatment of neonatal ARDS
Objective:To investigate the application effect of pulmonary surfactant(PS)modified drug administration combined with flow continuous positive airway pressure(CPAP)ventilator in neonates with acute respiratory distress syndrome(ARDS).Methods:72 neonates with ARDS admitted to our hospital from January 2020 to August 2022 were selected as subjects,and they were randomly divided into observation group and control group,with 36 cases in each group.The control group was treated with conventional therapy and flow CPAP ventilator,while the observation group was treated with PS modified medication on the basis of the control group.The results of blood gas analysis,therapeutic effect and complications were compared between the two groups.Results:Compared with the control group,the observation group showed improvements in lung ventilation and oxygenation function,shorter hospital stay and ventilation time,higher overall treatment efficiency,and lower incidence of complications(P<0.05).Conclusion:Modified PS administration and flow CPAP ventilator can improve lung ventilation and oxygenation function in children with ARDS,promote recovery,reduce complications,and have significant clinical efficacy.