Relationship between chest CT and serum TLRs,sTREM-1 expression and prognosis in children with mycoplasma pneumonia
Objective:To study the relationship between chest CT and expression of TLRs,sTREM-1 and prognosis in children with Mycoplasma pneumoniae pneumonia.Methods:In this study,a total of 204 children diagnosed with mycoplasma pneumoniae pneumonia and admitted between May 2019 and January 2022 were enrolled.Based on the severity of their condition,the patients were categorized into two groups:the normal group and the severe group.Subsequently,a comparative analysis was conducted to assess the levels of chest CT scores,TLRs,and sTREM-1 between the two groups.The Pearson correlation method was employed to evaluate the relationship between chest CT scores and TLRs,as well as sTREM-1.Follow-up assessments were performed over a period of 6 months,classifying the patients into either a good prognosis group or a poor prognosis group.Logistic regression analysis was employed to identify the influencing factors associated with poor prognosis,and the diagnostic efficiency was assessed by constructing ROC curve.Results:CT scores,TLR5 and sTREM-1 in the severe group were significantly higher than those in the common group.Logistic regression analysis showed that CT score,TLR2,TLR4,TLR5 and sTREM-1 were the influencing factors of poor prognosis.ROC curve showed that the sensitivity and specificity of combined diagnosis were higher than those of single detection(P<0.05).Conclusion:Chest CT score,TLR2,TLR4,TLR5,sTREM-1 and Logistic regression analysis can be used to predict and diagnose the poor prognosis of mycoplasma pneumonia.
万方数据
维普
