CT结合血清肿瘤标志物鉴别肝硬化结节与小肝癌的作用

Value of CT combined with serum tumor markers in the differential diagnosis of cirrhosis nodules and small hepatocellular carcinoma

马丽娜 ¹魏长春 ¹贺利 ¹栗师 ¹乔龙虎¹

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作者信息

1. 亳州市中医院 236800
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摘要

分析计算机断层扫描(CT)结合血清癌抗原 19-9(CA19-9)、癌胚抗原(CEA)、甲胎蛋白(AFP)对104 例肝硬化结节与小肝癌患者的诊断价值.所有患者接受腹部CT平扫及增强扫描,检测血清CA19-9、CEA、AFP水平.结果表明,CT 结合血清 CA19-9、CEA、AFP 预测小肝癌的 AUC 为 0.891,敏感度为 85.90%(P＜0.05).CT结合血清CA19-9、CEA、AFP在鉴别诊断肝硬化结节和小肝癌中具有较高的敏感度,可作为临床鉴别肝硬化结节和小肝癌的有效手段.

Abstract

To analyze the diagnostic value of computed tomography(CT)combined with serum carcinoembryonic antigen 19-9(CA19-9),Carcinoembryonic antigen(CEA)and alpha fetoprotein(AFP)in 104 patients with cirrhosis nodules and small liver cancer.All patients underwent abdominal CT plain and contrast-enhanced scans to detect serum levels of CA19-9,CEA,and AFP.The results showed that the AUC of small liver cancer predicted by CT combined with serum CA19-9,CEA,and AFP was 0.891,with a sensitivity of 85.90%(P<0.05).CT combined with serum CA19-9,CEA,and AFP has high sensitivity in differential diagnosis of liver cirrhosis nodules and small liver cancer,and can serve as an effective method for clinical differentiation of liver cirrhosis nodules and small liver cancer.

关键词

计算机断层扫描/癌抗原19-9/癌胚抗原/肝硬化结节/小肝癌

Key words

Computed tomography/Cancer antigen 19-9/Carcinoembryonic antigen/Cirrhosis nodule/Small hepatocellular carcinoma

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基金项目

亳州市科研基金(XMHRYXFN20210524)

出版年

2024

现代科学仪器

中国分析测试协会

现代科学仪器

CSTPCD

影响因子：0.329

ISSN：1003-8892

参考文献量25

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