自动凯氏定氮—电位滴定仪联合检测中药材中的二氧化硫
Rapid Determination of Sulfur Dioxide in Chinese Medicinal Materials by Automatic Kjeldahl Nitrogen Determination Potentiometric Titration
毕程程 1孙佳 1张恩旭 1孙玉 2赵庆松 3罗雁非3
作者信息
- 1. 延吉海关综合技术服务中心,延吉 133000
- 2. 吉林省中医药科学研究院,吉林长春 130013
- 3. 长春海关技术中心,吉林长春 130062
- 折叠
摘要
利用自动凯氏定氮仪对中药材样品进行蒸馏前处理,利用电位滴定仪滴定样品中的二氧化硫含量,再与《中华人民共和国药典》2020 版第四部通则 2331 第一法相比,测定结果无显著差异(P＞0.05).通过实验确定了使用凯氏定氮仪快速检测中药材样品二氧化硫的蒸馏时间、加水量等条件,该方法操作简单,实验过程仅需 8～10分钟,相对标准偏差小于 1.01%,加标回收率为 95.3～101.8%,适合应用于中药材样品大批量的检测.
Abstract
The samples of Chinese medicinal materials were pretreated before distillation with an automatic Kjeldahl nitrogen determinator,and the sulfur dioxide content in the samples was titrated with a potentiometric titrator.Compared with the first method of 2331,Part IV of the Pharmacopoeia of the People's Republic of China(2020),the determination results showed no significant difference(P>0.05).The conditions such as the distillation time and the amount of water added for the rapid detection of sulfur dioxide in Chinese herbal medicine samples with Kjeldahl nitrogen determination instrument were determined through experiments.This method is simple,the experimental process only takes 8 to 10 minutes,the relative standard deviation is less than 1.01%,and the recovery rate of spiking is 95.3 to 101.8%.It is suitable for the detection of large quantities of Chinese herbal medicine samples.
关键词
二氧化硫/全自动凯氏定氮仪/自动电位滴定仪/快速检测Key words
Sulfurdioxide/Fullautomatic Kjeldahl nitrogen analyzer/Automatic potentiometric titrator/Quick detection引用本文复制引用
基金项目
海南省重点研发计划(ZDYF2021SHFZ069)
出版年
2024
国家科技期刊平台
NSTL
万方数据