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CKD患者PTH水平与心功能、血钙、血磷水平的关系分析

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目的:探究PTH与CKD患者的心功能、血钙和血磷水平的关系。方法:选取 120 例CKD患者和同期 30例肾小球滤过率正常患者,收集心功能、PTH、血钙、血磷水平数据并分析各指标相关性。结果:CKD各期与对照组年龄、BMI、血钙和LVEF无显著差异(P>0。05),且血压、PTH、血磷、钙磷乘积和LVMI均高于对照组(P<0。05);PTH与LVMI、磷和钙磷乘积有显著正相关(P<0。05);多因素分析显示,PTH与LVMI、钙磷乘积、血压有明显正相关关系(P<0。05)。结论:CKD患者的PTH水平升高与血压、血磷、钙磷乘积及左心室重量相关。
Analysis of the relationship between PTH levels and cardiac function,blood calcium,and blood phosphorus levels in CKD patients
Objective:To investigate the relationship between serum PTH levels and cardiac function,serum calcium,and serum phosphorus levels in patients with CKD.Methods:A total of 120 patients with CKD and 30 patients with normal renal function were selected.Data on cardiac function,serum PTH,serum calcium,serum phosphorus levels were collected and the correlation between each index was analyzed.Results:There were no significant differences in age,BMI,serum calcium,and LVEF between the CKD groups and the control group(P>0.05).However,blood pressure,serum PTH,serum phosphorus,serum calcium-phosphorus product,and LVMI were higher in the CKD groups(P<0.05).Serum PTH levels were significantly positively correlated with LVMI,serum phosphorus,and serum calcium-phosphorus product(P<0.05).Multivariate analysis showed a significant positive correlation between serum PTH and LVMI,serum calcium-phosphorus product,and blood pressure(P<0.05).Conclusion:The elevated serum PTH levels in patients with CKD are associated with blood pressure,serum phosphorus,serum calcium-phosphorus product,and left ventricular mass.

Chronic kidney diseaseParathyroid hormoneHeart functionBlood calciumBlood phosphorus

赵莉、吴洁、张玉宝、刘雯雯

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合肥市第三人民医院肾内科,安徽合肥 230022

慢性肾脏病 甲状旁腺素 心功能 血钙 血磷

2024

现代科学仪器
中国分析测试协会

现代科学仪器

CSTPCD
影响因子:0.329
ISSN:1003-8892
年,卷(期):2024.41(2)
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