首页|PI、RI指数结合血清sFlt-1在子宫肌瘤患者中的诊断作用

PI、RI指数结合血清sFlt-1在子宫肌瘤患者中的诊断作用

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目的:探讨超声评价PI和RI结合sFlt-1诊断子宫肌瘤的临床价值。方法:选取 2020年 1月~2022年8月收治的 150例,怀疑患有子宫腺肌病或子宫肌瘤患者作为研究对象,计算PI和RI指数,检测患者血清sFlt-1水平。Logistic 回归模型结合 ROC 曲线评价各指标单独及联合检测对子宫肌瘤诊断的临床价值。结果:子宫肌瘤患者RI 及 PI 参数值均显著低于子宫腺肌病患者,而血清 sFlt-1 表达水平升高(P<0。001)。子宫动脉超声、血清 sFlt-1水平联合检测诊断效能高于单项检测(P<0。05)。结论:子宫动脉超声联合血清sFlt-1 检查可提高子宫肌瘤患者诊断的灵敏度和特异性,对于子宫肌瘤患者诊断具有潜在应用价值。
Diagnostic role of PI and RI index combined with serum sFlt-1 in patients with uterine fibroids
Objective:TTo evaluate the clinical diagnostic value of PI and RI combined with sFlt-1 in patients with uterine fibroids.Methods:150 patients suspected to have adenomyosis or uterine fibroids admitted from January 2020 to August 2022 were selected as research objects.PI and RI indexes were calculated to detect serum sFlt-1 levels of patients.Logistic regression model combined with ROC curve to evaluate the clinical value of single and combined detection of each indicator in the diagnosis of uterine fibroids..Results:The values of RI and PI parameters in patients with uterine fibroids were significantly lower than those in patients with adenomyosis,while serum sFlt-1 expression level was increased(P<0.001).The diagnostic efficacy of combined detection of uterine artery ultrasound and serum sFlt-1 was higher than that of single detection(P<0.05)..Conclusion:Uterine artery ultrasound combined with serum sFlt-1 can improve the sensitivity and specificity of the diagnosis of uterine leiomyoma patients,which has potential application value for the diagnosis of uterine leiomyoma patients.

Uterine leiomyomaAdenomyosisUterine artery ultrasoundBeat indexResistance indexSoluble vascular endothelial growth factor receptor-1diagnostic value

张宇函、刘鑫、马红玉

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邢台市中医院妇科,河北省邢台市 054001

邢台市中医院中西医结合外科,河北省邢台市 054001

子宫肌瘤 子宫腺肌病 子宫动脉超声 搏动指数 阻力指数 可溶性血管内皮生长因子受体-1 诊断价值

2024

现代科学仪器
中国分析测试协会

现代科学仪器

CSTPCD
影响因子:0.329
ISSN:1003-8892
年,卷(期):2024.41(3)