首页|血清UA、SOD水平与高原地区冠心病的相关性研究

血清UA、SOD水平与高原地区冠心病的相关性研究

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目的:探讨高原地区冠心病的发生与尿酸(UA)和超氧化物歧化酶(SOD)的相关性.方法:1491 例冠心病患者分为稳定性心绞痛(SAP)组、急性冠脉综合征(ACS)组,1394例正常人群为对照组,分析各组间尿酸、超氧化物歧化酶的差异性.结果:冠心病组中UA高于对照组,而SOD低于对照组,差异性有统计学意义(t=6.896、-8.594,P<0.05).ACS组SOD低于SAP组,差异有统计学意义(F=24.536,155.212,P<0.05).结论:冠心病发生的风险随着尿酸升高而增加,随着超氧化物歧化酶水平减低而增高,两者可作为评估发生冠心病风险的重要指标.
Correlation between serum UA and SOD levels and coronary heart disease in plateau area
Objective:To investigate the correlation between coronary heart disease(CHD)and uric acid(UA)and superoxide dismutase(SOD)in plateau area.Methods:1491 patients with CHD were divided into stable angina pectoris(SAP)group,acute coronary syndrome(ACS)group and 1394 normal people as control group.The differences of uric acid and superoxide dismutase among all groups were analyzed.Results:UA in CHD group was higher than that in control group,SOD was lower than that in control group,the difference was statistically significant(t=6.896,-8.594,P<0.05).SOD in ACS group was lower than that in SAP group,and the difference was statistically significant(F=24.536,155.212,P<0.05).Conclusion:The risk of coronary heart disease increases with the increase of uric acid and the increase with the decrease of superoxide dismutase,both of which can be used as important indicators to assess the risk of coronary heart disease.

uric acidSuperoxide dismutaseCoronary heart diseaseAcute coronary syndromeStable angina pectoris

曹建东、马晓峰、邓勇、王红、周巍

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青海省心脑血管病专科医院心内科,青海 西宁 810012

尿酸 超氧化物歧化酶 冠心病 急性冠脉综合征 稳定性心绞痛

2024

现代科学仪器
中国分析测试协会

现代科学仪器

CSTPCD
影响因子:0.329
ISSN:1003-8892
年,卷(期):2024.41(6)