Factors and interventions of multidrug-resistant bacterial infections in patients with chronic obstructive pulmonary disease(COPD)undergoing non-invasive ventilation
Objective:To the factors and intervention measures for multidrug-resistant bacterial infections in hospitalized patients with chronic obstructive pulmonary disease(COPD)complicated by respiratory failure undergoing non-invasive ventilation.Methods:Collect 100 patients with chronic obstructive pulmonary disease(COPD)and respiratory failure treated with non-invasive ventilation from June 2021 to May 2023,explore the influencing factors through multivariate logistic analysis,construct a predictive model,and evaluate the effectiveness.Results:The infection rate of multidrug-resistant bacteria was 22%,and univariate analysis revealed six significant differences(P<0.05).Multivariate analysis identified smoking history,long-term hormone inhalation,and antibiotic type as influencing factors(P<0.05).ROC analysis showed that the AUC of the three factors were 0.393,0.899,and 0.771,respectively.The AUC of the combined diagnosis increased to 0.955,with a sensitivity of 100%and a specificity of 82.1%.Conclusion:Smoking history,hormone inhalation,and antibiotic type affect multidrug-resistant bacterial infections in patients with chronic obstructive pulmonary disease.Controlling these factors can prevent infection,improve efficacy and safety.
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