Analysis of unexpected antibody distribution and transfusion efficacy in patients undergoing cardiovascular surgery with proposed blood transfusion
Objective:to explore the distribution of accidental antibodies and the efficacy of blood transfusion in patients with cardiovascular surgery intended for blood transfusion.Methods:1260 patients who underwent cardiovascular surgery in our hospital from April 2020 to April 2024 were selected to compare the efficacy of blood transfusion therapy.Results:Out of 1260 hospitalized patients,38(3.02%)tested positive for irregular antibodies in their serum.The positive rate of irregular antibodies in the ineffective transfusion group(23.15%)was significantly higher than that in the effective transfusion group(1.13%)(P<0.05).Irregular antibody positivity is an independent risk factor for ineffective blood transfusion in patients undergoing cardiovascular surgery(OR=3.974,P<0.05).Conclusion:For patients undergoing cardiovascular surgery,especially for females with multiple pregnancies and transfusion histories,it is necessary to strengthen the testing of Rh,MNSs,Lewis and other blood type systems to improve the recognition rate of irregular antibodies.