现代科学仪器2024,Vol.41Issue(6) :316-321.

大肠侧向发育型肿瘤分型中蓝光成像与化学染色技术应用

Application of blue light imaging and chemical staining techniques in the classification of laterally spreading tumor of the large intestine

许家珂 赵坚敏 蔡丽莉
现代科学仪器2024,Vol.41Issue(6) :316-321.

大肠侧向发育型肿瘤分型中蓝光成像与化学染色技术应用

Application of blue light imaging and chemical staining techniques in the classification of laterally spreading tumor of the large intestine

许家珂 1赵坚敏 1蔡丽莉1
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作者信息

  • 1. 昆山市第二人民医院消化内科,江苏 苏州 215300
  • 折叠

摘要

目的:探究亮蓝光成像模式(BLI-bright)联合化学染色技术在大肠侧向发育型肿瘤(LST)分型中的诊断价值.方法:选取 2021 年 1 月-2024 年 1 月收治的LST的 150 例(168 处病变)患者,行BLI-bright联合化学染色技术检查,比较和术后病理结果一致性.结果:BLI-bright+化学染色分型:各类型肿瘤的诊断灵敏度介于 50.00%(ⅢS型对SMd)至 90.68%(ⅢL型、Ⅳ型对LGD/HGD),特异度在 78.00%(ⅢL型、Ⅳ型)至98.75%(ⅢS型)间.联合诊断时,灵敏度和特异度分别可达 100.00%和 96.88%,整体准确度 91.67%-97.02%,AUC 0.741-0.984,Kappa 0.512-0.747.结论:BLI-bright联合化学染色技术能准确展现LST的Pit分型微小结构,具备肿瘤良恶性判断的高临床应用价值.

Abstract

Objective:To investigate the diagnostic value of blue light imaging(BLI-bright)combined with chemical staining techniques in the classification of lateral spreading tumor(LST)of the large intestine.Methods:150 patients(with 168 lesions)diagnosedwith LST admitted from January 2021 to January 2024,and performed BLI-bright combined with chemical staining technique examination.We compared the consistency between the results and postoperative pathological findings.Results:BLI-bright+chemical staining typing:The diagnostic sensitivity for various types of tumors ranged from 50.00%(type ⅢS vs.SMd)to 90.68%(types ⅢL and Ⅳ vs.LGD/HGD),with specificity ranging from 78.00%(types ⅢL and Ⅳ)to 98.75%(type ⅢS).When combined with diagnosis,the sensitivity and specificity could reach 100.00%and 96.88%,respectively,with overall accuracy ranging from 91.67%to 97.02%,AUC ranging from 0.741 to 0.984,and Kappa ranging from 0.512 to 0.747.Conclusion:BLI-bright combined with chemical staining technology can accurately reveal the Pit-type microstructure of LST,which holds high clinical application value in determining the benign or malignant nature of tumors.

关键词

亮蓝光成像/化学染色技术/大肠侧向发育型肿瘤/分型

Key words

Bright blue light imaging/chemical staining technique/lateral developmental tumors of the large intestine/staging

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出版年

2024
现代科学仪器
中国分析测试协会

现代科学仪器

CSTPCD
影响因子:0.329
ISSN:1003-8892
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