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大肠侧向发育型肿瘤分型中蓝光成像与化学染色技术应用

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目的:探究亮蓝光成像模式(BLI-bright)联合化学染色技术在大肠侧向发育型肿瘤(LST)分型中的诊断价值。方法:选取 2021 年 1 月-2024 年 1 月收治的LST的 150 例(168 处病变)患者,行BLI-bright联合化学染色技术检查,比较和术后病理结果一致性。结果:BLI-bright+化学染色分型:各类型肿瘤的诊断灵敏度介于 50。00%(ⅢS型对SMd)至 90。68%(ⅢL型、Ⅳ型对LGD/HGD),特异度在 78。00%(ⅢL型、Ⅳ型)至98。75%(ⅢS型)间。联合诊断时,灵敏度和特异度分别可达 100。00%和 96。88%,整体准确度 91。67%-97。02%,AUC 0。741-0。984,Kappa 0。512-0。747。结论:BLI-bright联合化学染色技术能准确展现LST的Pit分型微小结构,具备肿瘤良恶性判断的高临床应用价值。
Application of blue light imaging and chemical staining techniques in the classification of laterally spreading tumor of the large intestine
Objective:To investigate the diagnostic value of blue light imaging(BLI-bright)combined with chemical staining techniques in the classification of lateral spreading tumor(LST)of the large intestine.Methods:150 patients(with 168 lesions)diagnosedwith LST admitted from January 2021 to January 2024,and performed BLI-bright combined with chemical staining technique examination.We compared the consistency between the results and postoperative pathological findings.Results:BLI-bright+chemical staining typing:The diagnostic sensitivity for various types of tumors ranged from 50.00%(type ⅢS vs.SMd)to 90.68%(types ⅢL and Ⅳ vs.LGD/HGD),with specificity ranging from 78.00%(types ⅢL and Ⅳ)to 98.75%(type ⅢS).When combined with diagnosis,the sensitivity and specificity could reach 100.00%and 96.88%,respectively,with overall accuracy ranging from 91.67%to 97.02%,AUC ranging from 0.741 to 0.984,and Kappa ranging from 0.512 to 0.747.Conclusion:BLI-bright combined with chemical staining technology can accurately reveal the Pit-type microstructure of LST,which holds high clinical application value in determining the benign or malignant nature of tumors.

Bright blue light imagingchemical staining techniquelateral developmental tumors of the large intestinestaging

许家珂、赵坚敏、蔡丽莉

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昆山市第二人民医院消化内科,江苏 苏州 215300

亮蓝光成像 化学染色技术 大肠侧向发育型肿瘤 分型

2024

现代科学仪器
中国分析测试协会

现代科学仪器

CSTPCD
影响因子:0.329
ISSN:1003-8892
年,卷(期):2024.41(6)