Changes of serum soluble intercellular adhesion molecule-1 and visinin-like protein-1 levels in elderly patients undergoing hip replacement and their relationship with cognitive function
Changes of serum soluble intercellular adhesion molecule-1 and visinin-like protein-1 levels in elderly patients undergoing hip replacement and their relationship with cognitive function
韩杰 1张鹏 1斯焱 1毕梦娜 1张上上 1马邹 1王一臣 1张翔
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作者信息
1. 四川省骨科医院老年骨科1，成都 610041
折叠
摘要
探讨老年髋关节置换术患者血清可溶性细胞间黏附分子-1（sICAM-1）、视锥蛋白样蛋白-1（VILIP-1）水平变化及与认知功能的关系。研究显示认知障碍组患者血清sICAM-1、VILIP-1水平高于认知正常组，MMSE评分低于认知正常组（P<0.05）。血清sICAM-1、VILIP-1均为影响老年髋关节置换术患者发生认知功能障碍的相关因素（P<0.05）。 To investigate the changes of serum soluble intercellular adhesion molecule-1 (sICAM-1), visual cone like protein-1 (VILIP-1) and their relationship with cognitive function in elderly patients undergoing hip replacement. Research show:serum sICAM-1 and VILIP-1 were the related factors affecting cognitive dysfunction in elderly patients with hip replacement (P<0.05). The levels of sICAM-1 and VILIP-1 in serum of elderly patients with hip arthroplasty increased, and there was a certain relationship between them and their cognitive function.
Abstract
To investigate the changes of serum soluble intercellular adhesion molecule-1 (sICAM-1), visual cone like protein-1 (VILIP-1) and their relationship with cognitive function in elderly patients undergoing hip replacement. Research show:serum sICAM-1 and VILIP-1 were the related factors affecting cognitive dysfunction in elderly patients with hip replacement (P<0.05). The levels of sICAM-1 and VILIP-1 in serum of elderly patients with hip arthroplasty increased, and there was a certain relationship between them and their cognitive function.
关键词
髋关节置换术/老年人/血管性痴呆/认知功能障碍/认知功能
Key words
Hip replacement/Aged/Vascular dementia/Cognitive dysfunction/Cognitive function
万方数据