Expression of YKL-40, SerpinB1 and Betatrophin in serum of patients with gestational diabetes mellitus and their relationship with insulin resistance
张秋妍 1郭慧涛 1毕慧霞 1朱改变 2张翔
扫码查看
点击上方二维码区域，可以放大扫码查看
作者信息
1. 1山西省儿童医院 山西省妇幼保健院妇产保健综合门诊，太原 030006
2. 2山西省儿童医院 山西省妇幼保健院产科，太原 030006
折叠
摘要
研究妊娠期糖尿病（GDM）患者血清中人软骨糖蛋白39（YKL-40）、弹性蛋白酶抑制剂（SerpinB1）、血清促代谢因子（Betatrophin）的表达及其与胰岛素抵抗的关系。研究发现GDM患者血清中YKL-40、SerpinB1、betatrophin的表达与胰岛素抵抗呈现出显著的相关性，可为临床诊断提供科学依据。 To investigate the expression of human cartilage glycoprotein 39 (YKL-40), elastase inhibitor (SerpinB1) and serum pro-metabolic factor (Betatrophin) in the serum of patients with gestational diabetes mellitus (GDM) and their relationship with insulin resistance. The expression of YKL-40, SerpinB1 and betatrophin in the serum of GDM patients showed a significant correlation with insulin resistance, which could provide a scientific basis for clinical diagnosis.
Abstract
To investigate the expression of human cartilage glycoprotein 39 (YKL-40), elastase inhibitor (SerpinB1) and serum pro-metabolic factor (Betatrophin) in the serum of patients with gestational diabetes mellitus (GDM) and their relationship with insulin resistance. The expression of YKL-40, SerpinB1 and betatrophin in the serum of GDM patients showed a significant correlation with insulin resistance, which could provide a scientific basis for clinical diagnosis.
万方数据