The effects of whole-body vibration on postmenopausal women with osteoporosis: a Meta-analysis
于姗 1黑静友 2陈媛媛 3高呈飞 4王馨
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作者信息
1. 1聊城市第二人民医院内分泌科，聊城 252699
2. 2聊城市第二人民医院关节外科，聊城 252699
3. 3聊城市第二人民医院神经外科，聊城 252699
4. 4青岛大学附属医院康复医学科，青岛 266001
折叠
摘要
目的 系统评价全身振动（WBV）疗法对绝经后骨质疏松（PMOP）妇女的治疗效果。 方法 检索中国知网、万方、维普、PubMed、EMBASE、The Cochrane Library、Web of science等数据库，限定检索时间从数据库建立到2022年12月。筛选符合纳入标准的文献并进行数据提取，采用STATA软件进行meta分析。 结果 最终纳入10项随机对照研究，共计677名患者。Meta分析结果显示：WBV可以显著提高PMOP妇女的腰椎骨密度（BMD）[加权均数差（WMD）=0.024，95%CI：0.002~0.045，P=0.032]、股骨颈BMD（加权均数差WMD=0.040，95%CI：0.017~0.063，P=0.001）及疼痛评分[标准化均数差（SMD）=-0.786，95%CI：-1.300~-0.272，P=0.002）]，但对患者脂肪质量（WMD=1.028，95%CI：-4.811~2.755，P=0.572）、肌肉质量（WMD=0.632，95%CI：-1.437~2.700，P=0.563）无显著作用。 结论 WBV训练能够提高PMOP妇女BMD并减轻疼痛，但对患者脂肪及肌肉含量无影响。 Objective To comprehensively evaluate the therapeutic effects of whole-body vibration (WBV) training on women with postmenopausal osteoporosis (PMOP) . Methods The CNKI, Wanfang, VIP, PubMed, EMBASE, Cochrane Library, Web of Science databases were searched from database establishment to December 2022. Two independent researchers screened the articles and extracted data according to the inclusion and exclusion criteria. The data were extracted for meta-analysis using STATA software. Results Ten randomized controlled trials with a total of 677 patients were included. The meta-analysis results showed that WBV can significantly increase lumbar spine bone mineral density (BMD) (WMD=0.024, 95%CI: 0.002~0.045, P=0.032) , femoral neck BMD (WMD=0.040, 95%CI: 0.017~0.063, P=0.001) and reduce pain score (SMD=-0.786, 95%CI: -1.300~-0.272, P=0.002) in women with PMOP, but has no significant effect on patient’ fat mass (WMD=1.028, 95%CI: -4.811~2.755, P=0.572) and muscle mass (WMD=0.632, 95%CI: -1.437~2.700, P=0.563) . Conclusions WBV training can improve BMD and relieve pain in women with PMOP, but has no effect on patients’ fat mass and muscle mass.
Abstract
Objective To comprehensively evaluate the therapeutic effects of whole-body vibration (WBV) training on women with postmenopausal osteoporosis (PMOP) . Methods The CNKI, Wanfang, VIP, PubMed, EMBASE, Cochrane Library, Web of Science databases were searched from database establishment to December 2022. Two independent researchers screened the articles and extracted data according to the inclusion and exclusion criteria. The data were extracted for meta-analysis using STATA software. Results Ten randomized controlled trials with a total of 677 patients were included. The meta-analysis results showed that WBV can significantly increase lumbar spine bone mineral density (BMD) (WMD=0.024, 95%CI: 0.002~0.045, P=0.032) , femoral neck BMD (WMD=0.040, 95%CI: 0.017~0.063, P=0.001) and reduce pain score (SMD=-0.786, 95%CI: -1.300~-0.272, P=0.002) in women with PMOP, but has no significant effect on patient’ fat mass (WMD=1.028, 95%CI: -4.811~2.755, P=0.572) and muscle mass (WMD=0.632, 95%CI: -1.437~2.700, P=0.563) . Conclusions WBV training can improve BMD and relieve pain in women with PMOP, but has no effect on patients’ fat mass and muscle mass.
关键词
绝经后骨质疏松/全身振动/骨密度/Meta分析/随机对照试验
Key words
Postmenopausal osteoporosis/Whole-body vibration/Bone mineral density/Meta-analysis/Randomized controlled trials
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