外周血微RNA-223、Th1/Th2细胞与多囊卵巢综合征患者性激素水平和胰岛素抵抗的关系
Association of peripheral blood microRNA-223 and Th1/Th2 cells with sex hormone levels and insulin resistance in patients with PCOS
高洁凡 1黄晓 1宋阳阳 1王东晖 1张丹1
作者信息
- 1. 沧州市中心医院生殖医学科,沧州 061000
- 折叠
摘要
探讨外周微RNA-223(miR-223)、Th1/Th2细胞与多囊卵巢综合征(PCOS)患者性激素水平、胰岛素抵抗的关系.研究发现PCOS患者外周血miR-223、Th1/Th2细胞与性激素水平、胰岛素抵抗密切相关,且与疾病进展存在一定的关系,联合检测可提高PCOS的预测效能.
Abstract
To investigate the relationship between peripheral microRNA-223(miR-223),Th1/Th2 cells and sex hormone levels and insulin resistance in patients with polycystic ovary syndrome(PCOS).Peripheral blood mir-223 and Th1/Th2 cells in PCOS patients are closely related to sex hormone levels and insulin resistance,and there is a relationship with disease progression,and the combined test can improve the predictive efficacy of PCOS.
关键词
微RNA-223/Th1/Th2细胞/多囊卵巢综合征/性激素水平/胰岛素抵抗Key words
microRNA-223/Th1/Th2 cells/Polycystic ovary syndrome/Level of sex hormones/Insulin resistance引用本文复制引用
基金项目
河北省医学科学研究课题计划项目(20220341)
出版年
2023
NETL
NSTL
万方数据