现代泌尿生殖肿瘤杂志2024,Vol.16Issue(2) :70-74.DOI:10.3870/j.issn.1674-4624.2024.02.002

机器人辅助肾部分切除术出血性并发症预测因素分析

Predictive factors in hemorrhagic complications following robotic-assisted partial nephrectomy

林博涵 邱钱仁顺 高睿承 许宁 薛学义 孙雄林 郑清水 魏勇 陈少豪
现代泌尿生殖肿瘤杂志2024,Vol.16Issue(2) :70-74.DOI:10.3870/j.issn.1674-4624.2024.02.002

机器人辅助肾部分切除术出血性并发症预测因素分析

Predictive factors in hemorrhagic complications following robotic-assisted partial nephrectomy

林博涵 1邱钱仁顺 1高睿承 1许宁 1薛学义 1孙雄林 1郑清水 1魏勇 1陈少豪1
扫码查看

作者信息

  • 1. 350005 福州,福建医科大学附属第一医院泌尿外科
  • 折叠

摘要

目的 分析接受机器人辅助肾部分切除术(RAPN)的肾肿瘤患者发生出血性并发症(HCs)的风险预测因素.方法 分析2021年3月至2023年1月间接受RAPN的317例患者的临床、手术及术后病理资料,将术后血红蛋白下降>3 g/dl、术后需要输血、治疗性干预的动静脉瘘或假性动脉瘤的患者纳入出血组,其余纳入无出血组.通过倾向性评分匹配法(PSM)均衡组间混杂因素,通过单因素及多因素Logistic回归分析确定RAPN后HCs的独立预测因子.结果 纳入的317例患者中,29例患者术后出现HCs.经过PSM控制纳入研究参数的一致性,将27例RAPN后HCs与27例无HCs的患者进行匹配.单因素Logistic回归分析提示,R.E.N.A.L.评分≥10 分(OR=5.92,95%CI=2.36~14.82)、手术时间≥130 min(OR=6.21,95%CI=1.94~19.84)及热缺血时间≥23 min(OR=3.60,95%CI=1.42~9.13)是RAPN后HCs的影响因素,进一步多因素Logistic回归分析显示,R.E.N.A.L.评分≥10分(OR=5.03,95%CI=2.78~9.10)、手术时间≥130 min(OR=1.02,95%CI=1.01~1.03)及热缺血时间≥23 min(OR=1.15,95%CI=1.05~1.26)是RAPN后HCs的危险因素.结论 术前R.E.N.A.L.评分≥10分、手术时间≥130 min及热缺血时间≥23 min的患者更有可能在RAPN后发生HCs.

Abstract

Objective To analyze the predictive factors in hemorrhagic complications(HCs)following robot-assisted partial nephrectomy(RAPN)in renal tumor patients.Methods The bas-ic clinical,surgical,and postoperative pathological data of 317 patients undergoing RAPN between March 2021 and January 2023 were analyzed.Patients with postoperative hemoglobin decrease>3g/dl,arterial venous fistula or pseudoaneurysm requiring blood transfusion or therapeutic intervention were included in the bleeding group.Propensity score matching(PSM)balanced confounding factors between groups,and independent predictors of HCs after RAPN were determined through univariate and multivariate logistic regression analyses.Results Of the 317 patients included in this study,29(9.15%)had HCs.After ensuring parameter consistency through PSM control,27 cases of pa-tients with HCs after RAPN were matched with 27 cases of patients without HCs.Univariate logis-ticregression analysis showed that R.E.N.A.L.score≥ 10(OR=5.92,95%CI=2.36-14.82),surgical time≥130 minutes(OR=6.21,95%CI=1.94-19.84),and warm ischemia time≥23 mi-nutes(OR=3.60,95%CI=1.42-9.13)are significant factors influencing the occurrence of HCs after RAPN.Multivariate logistic regression analysis showed that R.E.N.A.L.score≥ 10(OR=5.03,95%CI=2.78-9.10),operative time≥130 minutes(OR=1.02,95%CI=1.01-1.03)and warm ischemia time≥23 minutes(OR=1.15,95%CI=1.05-1.26)were independent risk factors for HCs after RAPN.Conclusions Patients with preoperative R.E.N.A.L.score ≥10,operative time≥130 minutes and warm ischemia time≥23 minutes are more likely to have HCs after RAPN.

关键词

机器人辅助肾部分切除术/R.E.N.A.L评分/出血性并发症

Key words

Robot-assisted partial nephrectomy/R.E.N.A.L.score/Hemorrhagic complications

引用本文复制引用

出版年

2024
现代泌尿生殖肿瘤杂志
华中科技大学

现代泌尿生殖肿瘤杂志

CSTPCD
影响因子:0.403
ISSN:1674-4624
参考文献量19
段落导航相关论文