Synthesis and bactericidal activity of glucose thiazole derivatives
To develop green pesticides with novel structures,thiazole structure was introduced into furan glucose,and twenty nine glucose thiazole compounds were designed and synthesized.Their structures were characterized by 1H NMR,13C NMR,HRMS.The fungicidal activity tests showed that at the concentration of 50 μg/mL,the target compounds exhibited certain fungicidal activities against Botrytis cinerea,Fusarium oxysporum,Colletotrichum gloeosporioides,Colletotrichum fragariae,Fusarium moniliforme.The inhibition rates of some compounds were over 50％against Fusarium oxysporum,Colletotrichum gloeosporioides,and Colletotrichum fragariae.All the compounds had certain antifungal activities against Botrytis cinerea,especially compound F-4,with the inhibitory rate of 90.3％.
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