RNA biopesticides are polynucleotide preparations that inhibit the transcription or expression of specific genes in target organisms through naturally occurring RNA interference pathways,which is a new green biopesticide with enormous development and application potential.The mechanism of the three RNAi pathways,dsRNA/siRNA,miRNA,and piRNA were introduced in this paper.Then,the research progress and commercialization progress of dsRNA,miRNA biopesticides in the field of pest control,and the similarities and differences between dsRNA and miRNA biopesticides were summarized.Finally,the possible problems that might be encountered in the future application of RNA biopesticides were analyzed and reasonable suggestions were put forward.This review provided references for the research and application of RNA biopesticides,and offered new ideas for comprehensive pest control.
RNA biopesticideRNA interferencedouble stranded RNAmicroRNApest control