Study on synthesis of bixafen intermediate 2-(3,4-dichlorophenyl)-4-fluoroaniline
In this paper,the synthetic routes of bixafen intermediate 2-(3,4-dichlorophenyl)-4-fluoroaniline were studied.3,4-Dichlorophenylhydrazine was prepared from 3,4-dichloroaniline by diazotization and reduction reaction,and then it was coupled with 4-fluoroaniline in air under alkaline conditions to obtain the target product.The yield of the target product was above 80％,and the content was more than 90％,calculated by 3,4-dichloroaniline.Compared with other process routes,this route had the advantages of cheap raw materials,easy preservation,simple operation,high yield,and easy purification.
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维普
