In order to screen the nematocides with excellent efficacy against Ditylenchus destructor and suitable for application,the efficacies and economic benefits of 6 kinds of nematocide on Ditylenchus destructor were evaluated by root-dipping method in three different counties of Henan Province.The results showed that the sweet potato seedlings grew vigorously and the survival rates of each treatment were more than 95%.The efficacies of abamectin 5%CS,phoxim 30%CS and abamectin·fosthiazate 21%EW on Ditylenchus destructor were more than 80%,and the control effect of phoxim 30%CS was the best.All nematocides could reduce the rates of diseased plant and potato,increase the yield of healthy potatoes,with an averaged income of 107.50-855.00 yuan per 667 m2.Phoxim 30%CS was the most economical and effective nematicide against Ditylenchus destructor on sweet potato and could be promoted and applied in suitable areas.