霜脲氰的合成工艺改进
Improvement for the synthesis process of cymoxanil
徐宁 1李林虎 1许宜伟 1葛凤敏1
作者信息
- 1. 利民控股集团股份有限公司,江苏徐州 221400
- 折叠
摘要
针对目前霜脲氰合成工艺产品收率低、"三废"量大、安全性低等问题,开发了 一种改进的生产工艺.以1-氰乙酰基-3-乙基脲为原料,经与亚硝酸异丙酯肟化反应,然后在催化剂存在下,与氯甲烷进行甲基化反应,得到霜脲氰.在优化的工艺条件下,产品收率在95％以上,产品质量分数可达 99％.
Abstract
In view of the problems of low yield,large amounts of wastes and low safety,an improved synthesis process was developed.The target product cymoxanil was obtained by two steps,1-cyanoacetyl-3-ethyl urea reacted with isopropyl nitrite via oximation reaction,and then reacted with methyl chloride via methylation reaction in the presence of catalyst.The yield of the product was over 95％and the purity of the product was 99％under the optimized process conditions.
关键词
霜脲氰/亚硝酸异丙酯/氯甲烷/甲基化反应/工艺改进Key words
cymoxanil/isopropyl nitrite/methyl chloride/methylation reaction/process improvement引用本文复制引用
出版年
2024
NETL
NSTL
万方数据