Optimize MRI imaging techniques for experimental animal eyes
Objective The aim of this study was to enhance the accuracy of ocular disease research and facilitate the development of new therapeutic methods by improving magnetic resonance imaging(MRI)techniques for experimental animals'eyes.Methods Five healthy SD rats were selected and examined using a Bruker 7.0T MRI scanner.By employing precise localization and meticulous adjustment of scanning parameters,T2-weighted imaging(T2WI)and FLASH imaging techniques were compared to assess image quality.Results The study demonstrated that high-quality,consistently positioned ocular MRI images were successfully obtained using a rat head coil combined with precise localization techniques.Comparatively,the FLASH sequence exhibited a higher signal-to-noise ratio(SNR)in ocular structural imaging than the T2WI sequence,thereby providing clearer images and more detailed tissue information.Conclusion This research successfully improved the quality of ocular MRI imaging and confirmed the superiority of the FLASH technique in ophthalmic research.It lays a solid technical foundation for future clinical applications and opens up new possibilities for the application of MRI technology in other fields.
Magnetic resonance imagingMRI SequencesSignal-to-noise ratioOcular structuresRatsMRI scanning techniquesExperimental teaching
NETL
NSTL
万方数据
