Clinical value of three phase bone scintigraphy semi-quantitative analysis in differentiating recurrence and infection after malignant bone tumor operation
Objective To explore the clinical value of three phase bone scintigraphy semi-quantitative analysis in differentiating recurrence and infection after malignant bone tumor operation.Methods A retrospective analysis was performed on 29 patients who underwent three phase bone scintigraphy semi-quantitative analysis after operation of malignant bone tumors.Two experienced nuclear medicine physicians independently and blindly read the films by three-phase bone imaging visual analysis and semi-quantitative analysis.To obtain the semi-quantitative indexes of three-phase bone imaging.Use the ROC curve and t test to statistical analysis.Results The specificity of three phase bone scintigraphy in the diagnosis of postoperative recurrence and infection was low(27.27%).The diagnostic accuracy of the average radioactivity count of the affected side in blood flow and the slope of the radioactivity counting rate-time curve slope was the highest in the semi-quantitative analysis of three phase bone scintigraphy.When the average radioactivity count of blood flow was larger than 2.9 or the slope rate of radioactivity counting rate-time curve was more than 2.95,it was possible to consider the lesion for recurrence.Conclusion The semi-quantitative analysis of three-phase bone imaging can more accurately reflect the blood perfusion situation of the lesion site,which plays an important role in the early detection of postoperative recurrence of malignant bone tumors.
Three phase boneSemi-quantitative analysisBone tumorRecurrenceInfection