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基于ArcCheck模体放疗计划的验证与分析

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目的 为了保证放疗剂量输出的准确性,对放疗患者的临床放疗计划进行了验证与分析。方法 选取2023 年7-10 月南方医科大学珠江医院放疗患者的临床放疗计划,共217 例计划,其中头颈部 76 例,胸部 82 例,腹盆部 59 例。采用美国SunNuclear公司的ArcCheck模体,比较临床放疗计划与验证计划的剂量学差异。采用T test分析在不同容许剂量差值和不同容许距离差值下的Gamma通过率,ANOVA test比较在相同条件下,不同放疗部位放疗计划的Gamma通过率。所有数据分析采用IBM公司的SPSS v27。0 完成。结果 在容许剂量差值为3%,容许距离差值为3。0mm和在容许剂量差值为2%,容许距离差值为2。0mm下的Gamma通过率比较,差异有统计学意义(P<0。05)。在相同容许剂量差值和容许距离差值下,不同放疗部位的Gamma通过率比较,差异无统计学意义(P>0。05)。结论 在容许剂量差值为3%,容许距离差值为3。0mm的条件下,放疗计划的Gamma通过率显著高于容许剂量差值为2%,容许距离差值为2。0mm条件下的计划Gamma通过率,并且条件设置越严格,Gamma通过率越低。在相同容许剂量差值和容许距离差值下,不同放疗部位放疗计划的Gamma通过率不存在显著性差异。Gamma通过率受容许剂量差值和距离差值的影响,同时做好对直线加速器,计划系统等的日常的质量控制与保证也能提高Gamma通过率。
Application of ArcCheck for validation and analysis of radiation plans
Objective In order to ensure the accuracy of radiotherapy dose delivery,the clinical radiotherapy plan of radiotherapy patients was verified and analyzed.Methods 217 radiation plans from July to October had been analysed,including 76 head and neck radiation plans,82 thorax radiation plans and 59 abdomen and pelvic radiation plans.ArcCheck phantom from SunNuclear company had been used to compare the dose difference of clinical radiation plans and validation radiation plans.Gamma passing rate under dose difference and distance difference had been compared by using T test,ANOVA test had been used to compare Gamma passing rate of different tumour radiation plans.All data analysis had been completed by SPSS V27.0 from IBM company.Results There was significant difference in Gamma pass rate between the tolerated dose difference of 3%and the tolerated distance difference of 3.0mm and the tolerated dose difference of 2%and the tolerated distance difference of 2.0mm(P<0.05).At the same permissible dose difference and permissible distance difference,there was no significant difference in Gamma passing rate of different radiotherapy sites(P>0.05).Conclusion Gamma passing rate under 3%dose difference and 3mm distance difference is significantly better than 2%dose difference and 2mm distance difference.Gamma passing rate would be lower when dose difference and distance difference have been limited.There is no significant difference of Gamma passing rate between different tumour radiation plans.Gamma passing rate is not only effected by dose difference and distance difference,but also will be improved by regular quality assurance of linear accelerator and treatment planning system.

Intensity-modulated radiotherapyArccheck phantomRadiation plansDose validationGamma passing rate

蔡丹婷

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南方医科大学珠江医院放疗科,广州 510282

调强放射治疗 ArcCheck模体 放疗计划 剂量验证 Gamma通过率

2024

现代仪器与医疗
中国科学器材公司

现代仪器与医疗

影响因子:1.47
ISSN:2095-5200
年,卷(期):2024.30(3)