基于纳米复合材料修饰微针的pH值实时检测电化学生物传感器
Electrochemical biosensor based on nanocomposites-modified microneedle for real-time monitoring of pH value
明涛 1兰婷婷 1于明星 1孔德领1
作者信息
- 1. 南开大学移植医学研究院,天津 300071
- 折叠
摘要
为了更好的监控人体生理状态,本文提出了一种基于纳米复合材料修饰微针的生物传感器研制策略.通过精巧设计与高性能纳米功能膜的构建,基于不锈钢针与金丝微针基底研制了两种各具优势的pH值实时检测传感器,实现了对pH值的实时检测.结果表明,生物传感器具有毫伏级输出电压,响应时间在秒级.综上,本文所提出的纳米微针生物传感器具有高灵敏,微创,响应迅速和结构简单的优点,可以有效地实现对pH的实时检测.
Abstract
To better monitor the physiological state of the human body,this paper proposes a biosensor development strategy based on nanocomposite-modified microneedles.Through sophisticated design and the construction of high-performance nanomembranes,two pH real-time monitoring sensors with distinct advantages were developed using stainless steel needles and gold wire microneedles,achieving real-time pH detection.The results indicate that the biosensor produces a millivolt output voltage and has a response time of just a few seconds.In summary,the nanomaterial-modified microneedle biosensor proposed in this paper offers high sensitivity,minimal invasiveness,rapid response,and simple structure,effectively enabling real-time pH monitoring.
关键词
实时检测/生物传感器/微创探针/纳米材料/电化学Key words
Real-time monitoring/Biosensor/Minimally invasive probe/Nano materials/Electrochemical引用本文复制引用
基金项目
国家重大科研仪器研制项目(82127808)
出版年
2024
NETL
NSTL
万方数据