Effect of ROSE technique combined with electronic bronchoscopy on positive rate of bacterial culture,inflammatory index and curative effect in patients with multi-drug resistant infection
Objective To investigate the effect of ROSE technology combined with electronic bronchoscopy on the positive rate of bacterial culture,inflammatory index and therapeutic effect of patients with multi-drug resistant infection,and to provide reference for clinical application.Methods From January 2023 to November 2024,a total of 80 patients were hospitalized in the intensive care unit of Xinjiang Production and Construction Corps Hospital with a final diagnosis of multidrug resistant infection and underwent electronic bronchoscopy during hospitalization.Whether the citrus received ROSE intervention was divided into ROSE group and ROSE group.The ROSE group only underwent electronic bronchoscopy(Olympus,BF-Q290)during hospitalization.ROSE group underwent ROSE technique combined with electronic bronchoscopy during hospitalization.The negative conversion rate,colonization rate,infection rate,total hospitalization cost,hospital stay,antibiotic use time,clinical efficacy,inflammation and other indicators of the two groups were compared.Results After treatment,the negative conversion rate of bacteria in ROSE group was higher than that in ROSE group without treatment,and the colonization rate and infection rate were lower than that in ROSE group without treatment,with statistical significance(P<0.05).The indexes of total hospitalization cost,hospitalization days and antibiotic use time in ROSE group were lower than those in ROSE group without treatment,and the difference was statistically significant(P<0.05).The total effective rate of ROSE group was 97.50%,which was higher than that of ROSE group(75.00%),and the difference was statistically significant(P<0.05).After treatment,CRP,IL-4,IL-6 and other indexes in ROSE group were lower than those in ROSE group without treatment,and the difference was statistically significant(P<0.05).Conclusion ROSE technique is helpful to increase bacterial negative conversion rate,reduce colonization rate and infection rate in patients with multi-drug resistant infection who underwent electronic bronchoscopy,and it has significant effects,saves total hospitalization cost,shortens hospitalization days and antibiotic use time,and improves CRP,IL-4,IL-6 and other indicators.
ROSE technologyElectronic bronchoscopeMultidrug resistant infectionIntensive care unit
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NSTL
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