现代仪器与医疗2024,Vol.30Issue(5) :24-29.DOI:10.11876/mimt202405004

3D打印医用多孔钛合金阳极氧化修饰及其性能研究

Study on anodic oxidation modification and properties of 3D printed porous medical titanium alloy

黄朝阳 甄珍 王健 王浩 张芹 魏崇斌
现代仪器与医疗2024,Vol.30Issue(5) :24-29.DOI:10.11876/mimt202405004

3D打印医用多孔钛合金阳极氧化修饰及其性能研究

Study on anodic oxidation modification and properties of 3D printed porous medical titanium alloy

黄朝阳 1甄珍 2王健 3王浩 1张芹 1魏崇斌4
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作者信息

  • 1. 北京爱康宜诚医疗器材有限公司,北京 102200
  • 2. 中国医疗器械有限公司,北京 100028
  • 3. 中国食品药品检定研究院,北京 102629
  • 4. 北京爱康宜诚医疗器材有限公司,北京 102200;天衍医疗器材有限公司,常州 213149
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摘要

目的 探讨阳极氧化对3D打印多孔Ti-6Al-4V合金中Al/V金属离子的析出的影响.方法 采用阳极氧化对3D打印多孔Ti-6Al-4V合金进行表面修饰处理,研究阳极氧化前后,多孔Ti-6Al-4V合金的显微组织结构、表面形貌以及离子析出特性.结果 阳极氧化表面修饰并未改变多孔Ti-6Al-4V合金的α+β相组成,其表面形貌也未发生改变,合金表面成分中O元素含量增加6.48%,未引入非基体元素.阳极氧化显著降低了3D打印多孔Ti-6Al-4V合金中Al/V金属离子的析出,Hank′s溶液中浸提5周的结果显示,经阳极氧化后,Al离子析出溶度降低了93.4%,V离子析出浓度降低89.5%.结论 阳极氧化通过降低Al/V离子的析出,降低潜在毒性的风险,是进一步提高3D打印多孔Ti-6Al-4V钛合金植入器械安全性的有益途径.

Abstract

Objective To investigate the influence of anodic oxidation on the release of Al/V metal ions in 3D printed porous Ti-6Al-4V alloy.Methods The surface of 3D printed porous Ti-6Al-4V alloy was modified by anodic oxidation,and the microstructural organization,surface morphology,and ion release characteristics of the porous Ti-6Al-4V alloy before and after anodic oxidation were studied.Results Anodic oxidation surface modification did not change the α+β phase composition of the porous Ti-6Al-4V alloy,and its surface morphology was not changed.The O element content in the alloy surface increased by 6.48%,and no non-matrix elements were introduced.Anodic oxidation significantly reduced the release of Al/V metal ions in 3D printed porous Ti-6Al-4V alloy.The results of Hank's solution immersion for 5 weeks showed that after anodic oxidation,the solubility of Al ions was reduced by 93.4%,and the concentration of V ions was reduced by 89.5%.Conclusion Anodic oxidation,which reduces the release of Al/V ions and reduces the risk of potential toxicity,is a beneficial approach to further improve the safety of 3D printed porous Ti-6Al-4V titanium alloy implant devices.

关键词

3D打印/Ti-6Al-4V/阳极氧化/离子析出

Key words

3D printing/Ti-6Al-4V/Anodic oxidation/Ion precipitation

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基金项目

国家骨科与运动康复临床医学研究中心创新基金重点项目(NCRC-CXJJ-ZD1-1)

出版年

2024
现代仪器与医疗
中国科学器材公司

现代仪器与医疗

影响因子:1.47
ISSN:2095-5200
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