摘要
目的 分析并总结胃不适患者胃幽门螺旋杆菌流行病学特点.方法 收集 2023 年 4 月—2023 年 7 月期间在广州市越秀区东山街社区卫生服务中心因胃部不适来进行检测的患者312 例为研究对象,分析不同年龄、不同性别幽门螺旋杆菌阳性分布特点.结果 312 例患者中,阳性93 例,阴性219 例,阳性检出率为29.81%;其中,男性患者阳性28 例,阴性74 例,阳性检出率为27.45%;女性患者阳性65 例,阴性 145 例,阳性检出率为30.95%.不同性别阳性率差异无统计学意义(X2 =0.402,P=0.526);在男性感染者中,幽门螺旋杆菌检测DOB平均值为(23.01±26.75),在女性感染者中幽门螺旋杆菌检测DOB平均值为(17.31±11.84),其中DOB代表C13-尿素呼气试验超基准值(delta over baseline,DOB).男性DOB值高于女性,但差异无统计学意义(t =1.430,P=0.156);不同年龄阳性率分布无明显上升或下降趋势;阳性构成比以40 岁以上为主,占总阳性例数的 79.57%;年龄在 60 岁及以下阳性感染者中,幽门螺旋杆菌检测DOB平均值为(14.95±11.87),61 岁及以上阳性感染者中,幽门螺旋杆菌检测DOB平均值为(24.66±22.71).两组差异有统计学意义(t =2.643,P=0.009 7).结论 胃幽门螺旋杆菌在不同性别、年龄均可检出,是导致胃部不适的主要原因之一,社区开展C13 吹气实验可以早期检测有无感染,实现尽早进行抗生素治疗,从而降低胃部肿瘤发生率,充分体现社区卫生服务中心医防融合的服务理念.
Abstract
Objective To analyze and summarize the epidemiological characteristics of gastric Helicobacter pylori in pa-tients experiencing gastric discomfort in Yuexiu Dongshan Community,Guangzhou.Methods A total of 312 patients who visited Yuexiu District Dongshan Community Health Service Center for stomach upset testing between April 2023 and July 2023 were en-rolled in the study.The distribution characteristics of positive Helicobacter pylori were analyzed among the patients of different age and gender.Results Out of the 312 cases in the population,93 cases tested positive and 219 tested negative,with a positive de-tection rate of 29.81%.Specifically,28 cases tested positive,and 74 cases tested negative in the male population,with a positive detection rate of 27.45%.In the female population,65 cases tested positive,and 145 cases tested negative,with a positive detec-tion rate of 30.95%.The difference in positive rates by gender was not statistically significant(X2 =0.402,P=0.526).Among the male patients infected with Helicobacter,the mean value of delta over baseline of the C13 urea breath test(DOB)was(17.31±11.84).The DOB value was insignificantly higher in the males than in the females(t =1.430,P=0.156).There was no signifi-cant increasing or decreasing trend in the distribution of positive rates by age.The composition ratio of positive patients was predom-inant in the group aged 40 and above,accounting for 79.57%of the total number of positive cases.Among the individuals aged less than 60 infected with Helicobacter pylori,the mean duration of the breath test was(14.95±11.87),while among those aged over 61,the mean duration of the breath test was(24.66±22.71).The disparity between the two groups was statistically significant(t =2.643,P=0.009 7).Conclusion Gastric Helicobacter pylori can be detected in individuals of all genders and ages,and it is a primary cause of gastric discomfort.Community-based C13 breath tests can detect the presence of infections of helicobacter py-lori at an early stage.Antibiotics can be administered to treat the infections,thereby reducing the incidence of gastric tumors.
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