现代医院2024,Vol.24Issue(3) :490-492.DOI:10.3969/j.issn.1671-332X.2024.03.042

伴激素过敏史的结核性脑膜炎患者的激素治疗策略探讨

Hormone therapy for tuberculous meningitis patient with history of hormone allergy

周晓雯 周美辰 伍婉媚 钟洪兰
现代医院2024,Vol.24Issue(3) :490-492.DOI:10.3969/j.issn.1671-332X.2024.03.042

伴激素过敏史的结核性脑膜炎患者的激素治疗策略探讨

Hormone therapy for tuberculous meningitis patient with history of hormone allergy

周晓雯 1周美辰 1伍婉媚 1钟洪兰1
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作者信息

  • 1. 广州市胸科医院 广东广州 510095
  • 折叠

摘要

目的 旨在为伴有激素过敏史却需要使用激素治疗的患者提供用药参考和治疗思路.方法 药师结合说明书和文献,分析甲泼尼龙的致敏机制,辅助临床医生为伴有甲泼尼龙过敏史的结核性脑膜炎患者制定口服激素治疗方案,并对该方案的有效性和安全性进行验证.结果 甲泼尼龙注射制剂含有痕量的牛奶蛋白,禁用于已明确对牛乳过敏的患者.患者改为口服激素治疗后,未再出现过敏情况,病情平稳.结论 糖皮质激素本身也会诱发过敏反应,在病史采集过程中应关注患者既往过敏史,同时药师也可发挥药学特长,协助临床医生制定个体化给药方案,保障患者用药的有效性和安全性.

Abstract

Objective The aim is to provide drug regimen for patients who have hormone allergy history but need hor-mone therapy.Methods Pharmacists analyzed the sensitization mechanism of methylprednone in combination with insturction and literature,assisted clinicians to formulate oral hormone therapy for tuberculosis meningitis with history of menthylprednisolone and verified the effectiveness and safety of the drug regimen.Results Methylprednisolone injection contains trace amount of milk protein and should not be used in patients with definite allergy to cow's milk.After changing to oral hormone therapy,the patient did not appear allergic again,and the condition was stable.Conclusion Gucocorticoids can also induce allergic reactions,so patients'previous allergic history should be paid attention in the process of medical history collection.Meanwhile,pharmacists can also give full play to their pharmaceutical expertise to assist clinicians in formulating individualized drug administration plans to ensure the effectiveness and safety of patients.

关键词

结核性脑膜炎/甲泼尼龙/过敏

Key words

Tuberculous meningitis/Methylprednisolone/Allergy

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基金项目

广东省中医药局项目(20231269)

广州市卫生健康科技项目(20231A010032)

出版年

2024
现代医院
广东省医院协会

现代医院

影响因子:1.332
ISSN:1671-332X
参考文献量12
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