Objective:To investigate the value of dual source CT(DSCT)dual energy technique Rho/Z in differential diagnosis of benign and malignant solitary pulmonary nodules.Methods:130 patients with solitary pulmonary nodules underwent dual source CT dual energy scanning were analyzed retrospectively,including 68 cases in malignant group and 62 cases in benign group.The application Rho/Z was used to evaluate the unenhanced and enhanced venous phase images.Rho、Z and dual energy index(DEI)were recorded.The differences between the two groups were compared,and receiver operating characteristic(ROC)curve was drawn to evaluate the diagnostic efficacy of each parameter.Results:In unenhanced images,the Rho of the malignant group(31.1±22.33)HU was significantly higher than that of the benign group(24.69±20.91)HU,and there was a statistically significant difference between the two groups(P=0.003＜0.05),while there was no statistically significant difference in Z and DEI between the two groups(P＞0.05).In the enhanced venous phase images,the Rho of the malignant group(35.3±20.85)HU was significantly higher than that of the benign group(24.73±17.93)HU,and there was a statistically significant difference between the two groups(P=0.001＜0.05).There was no statistically significant difference in Z and DEI between the two groups(P＞0.05).In the differential diagnosis between the two groups,the area under the curve of Rho in unenhanced and enhanced venous phase were 0.652 and 0.696 respectively.Conclusion:DSCT with dual-energy technique Rho/Z have certain characteristics,which are helpful for the differentiation of benign and malignant solitary pulmonary nodules.
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