多模态超声对甲状腺微小乳头状癌术前预测研究
Preoperative Prediction of Thyroid Micropapillary Carcinoma by Multimodal Ultrasound
罗以恒 1黄莉丽1
作者信息
- 1. 东莞康华医院超声科(广东东莞 523000)
- 折叠
摘要
目的:评价常规超声(ultrasound,US)、超声造影(contrast-enhanced ultrasound,CEUS)和超声应变弹性成像(strain elastography,SE)在甲状腺微小乳头状癌(papillary thyroid microcarcinoma,PTMC)术前预测中的价值.方法:将75例PTMC患者共81个结节纳入研究,在术前接受常规US、CEUS、SE检查,采用多因素logis-tic回归分析评估PTMC的独立预测因子.评价常规超声、超声造影和SE的诊断性能.结果:高大于宽的甲状腺结节被认为是PTMC最强预测因子(odds ratio[OR],25.21),其次是不均匀强化(OR,22.01),弹性评分(OR,5.82),边界不清(OR,2.59)和年龄(OR,0.92).联合常规US、CEUS和SE预测PTMC,ROC曲线下面积为0.96,灵敏度为88.6％,特异性94.6％.结论:常规US联合CEUS、SE可提高PTMC诊断的准确率.
Abstract
Purpose:To evaluate the diagnostic value of conventional US,contrast-enhanced ultrasound(CEUS)and strain elastography(SE)for patients with papillary thyroid microcarcinoma(PTMC).Methods:In total,75 patients with 81 thyroid nodules who underwent conventional US,CEUS,and SE before surgery were enrolled.A multivariate logistic regression analysis was performed to assess the independent predictors of PTMC.Conventional US,CEUS and SE were combined to predict PTMCThe diagnostic performances of conventional US,CEUS,and SE were evaluated with a receiver operating characteristic(ROC)curve analysis.Results:A taller-than-wide shape was identified as the strongest predictor of PTMC(odds ratio[OR],25.21),followed by heterogeneous enhancement(OR,22.01),mean stain value value(OR,5.82),poorly defined margin(OR,2.59),and age(OR,0.92).When combined conventional US,CEUS and SE to predict PTMC,the area under the ROC curve was 0.96,the sensitivity was 88.6％,and the specificity was 94.6％.Conclusions:Conventional US combined with CEUS and RTE can improve the diagnostic accuracy of PTMC.
关键词
常规超声/超声造影/弹性成像/甲状腺微小乳头状癌Key words
ultrasound/contrast-enhanced ultrasound/strain elastography/papillary thyroid microcarcinoma引用本文复制引用
出版年
2024
NETL
NSTL
万方数据