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联合肝脏分隔和门静脉结扎二步肝切除术的研究进展

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联合肝脏分隔和门静脉结扎二步肝切除术(ALPPS)是近年来肝脏外科领域的一个技术创新,它可以在短时间内使剩余肝脏体积迅速增大,使原本因剩余肝脏体积不足而无法手术切除的肝肿瘤(特别是巨大肝癌)患者获得手术切除的机会.与传统二步肝切除术如门静脉栓塞、介入化疗栓塞、肝动脉结扎肿瘤降期后切除比较,ALPPS具有剩余肝脏体积增长速度快,两期手术间隔时间短,以及更高的可切除率等优势.但对于术后的长期疗效,尚无充分证据表明ALPPS优于传统二步肝切除术.
Research progress of associating liver partition and portal vein ligation for staged hepatectomy
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is an innovation in liver surgery in recent years.It provides opportunities of surgery for those with inadequate remnant liver volume by rapidly remnant liver hypertrophy.Comparing with conventional two stage hepatectomy (TSH),such as portal vein embolization,transcatheter arterial chemoembolization and hepatic artery ligation,ALPPS has advantages of fastened future liver remnant hypertrophy,shortened waiting time for the second stage of surgery and higher resection rate.But as for long-term curative effect,no strong evidence shows ALPPS is better than TSH.

Liver neoplasmsAssociating liver partition and portal vein ligation for staged hepatectomyLiver regenerationPrognosis

辛昊扬、王征、周俭

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复旦大学附属中山医院肝外科复旦大学肝癌研究所,上海200032

肝肿瘤 联合肝脏分隔和门静脉结扎的二步肝切除术 肝再生 预后

国家自然科学基金国家自然科学基金国家重点研发计划申康市级医院新兴前沿技术联合攻关项目

81572823817725782016YFC0902400SHDC12015104

2019

中华消化外科杂志
中华医学会

中华消化外科杂志

CSTPCDCSCD北大核心
影响因子:1.899
ISSN:1673-9752
年,卷(期):2019.18(2)
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