钇-90微球选择性内放射治疗肝脏恶性肿瘤规范化操作专家共识(2024版)
Expert consensus on the standardized procedure of selective internal radiation therapy with Yttrium-90 microspheres for liver malignancies(2024 edition)
中国医师协会介入医师分会临床诊疗指南专委会 中国研究型医院学会肝胆胰外科专业委员会 董家鸿 1滕皋军2
作者信息
- 1. 清华大学附属北京清华长庚医院肝胆胰外科,北京102218
- 2. 东南大学附属中大医院介入与血管外科 教育部医药基础研究创新中心,南京210009
- 折叠
摘要
钇-90微球选择性内放射治疗(90Y-SIRT)肝脏恶性肿瘤已有50余年临床应用史,大规模临床应用亦超过20年,其安全性和疗效已被证实,但在我国仍处于起步阶段.90Y-SIRT操作复杂,涉及多学科团队协作,对操作者要求较高,一旦发生90Y微球异位分布可能会导致严重并发症.因此,规范90Y-SIRT操作技术,对促进90Y-SIRT在我国稳步推广至关重要.中国医师协会介入医师分会临床诊疗指南专委会联合中国研究型医院学会肝胆胰外科专业委员会组织国内相关领域专家,基于现有文献证据并结合我国临床实践,围绕患者筛选、术前影像学评估、90Y-SIRT方案、处方剂量计算、90Y-SIRT实施、术后管理、常见不良反应与并发症等,共同制订本专家共识,规范90Y-SIRT操作,保证疗效,降低并发症发生率,促进90Y-SIRT在国内的推广和普及.
Abstract
Yttrium-90 microsphere selective internal radiation therapy(90Y-SIRT)has been used clinically for more than 50 years for liver malignancies,with confirmed safety and efficacy.Although it has been widely used for more than 20 years abroad,90Y-SIRT is just getting started in China.The procedure of 90Y-SIRT is relatively complex,which need multidisciplinary teamwork and higher requirements for operators.Once the ectopic distribution of 90Y microspheres occurs,it may lead to relatively serious complications.Therefore,it does need to standardize the procedure of 90Y-SIRT to ensure its efficacy,reduce the incidence of complications,and promote the popularization and application in China.It is for these reasons that experts from Chinese Medical Doctor Association,Clinical Guidelines Committee of Chinese College of Interventionalists and Society for Hepato-pancreato-biliary Surgery of Chinese Research Hospital Association formulate the Expert consensus based on the literature evidence and clinical practice,which including patient selection,preoperative imaging examination,aim of 90Y-SIRT,prescription dose calculation,90Y-SIRT protocol,postoperative manage-ment,common adverse reactions and complications,etc.
关键词
肝肿瘤/钇-90/微球/选择性内放射治疗/共识Key words
Liver neoplasms/Yttrium-90/Microsphere/Selective internal radiation therapy/Consensus引用本文复制引用
基金项目
国家自然科学基金(82130060)
国家自然科学基金(82372067)
国家重点研发计划(2018YFA0704100)
国家重点研发计划(2018YFA0704104)
江苏省影像医学与介入治疗医学创新中心(CXZX202219)
江苏高校放射医学协同创新中心()
南京市科技局生命健康科技专项医工结合项目(202205045)
出版年
2024
NETL
NSTL
万方数据