Objective To investigate the application value of laparoscopic-assisted total liver transplantation.Methods The retrospective and descriptive study was conducted.The clinical data of 9 pairs of donors and recipients who underwent laparoscopic-assisted total liver transplanta-tion in People's Hospital of Guangxi Zhuang Autonomous Region from January to April 2024 were collected.Of the donors,there were 8 males and 1 female,aged(39±18)years and with body mass index(BMI)of(20±4)kg/m2.Of the recipients,there were 7 males and 2 females,aged(41±13)years and with BMI of(24±4)kg/m2.Measurement data with normal distribution were represented as Mean±SD.Count data were described as absolute numbers.Results(1)Surgical conditions.Of the 9 recipients,7 recipients underwent laparoscopic-assisted total liver transplantation successfully,1 recipient with severe portal hypertension converted to open surgery with reverse L-shaped inci-sion due to the hemorrhage during the dissection of the first hepatic portal after completing liver mobilization under laparoscopy,and 1 recipient underwent trans-umbilical extension incision through the middle of the epigastric region due to the limited space for operation in the implantation of the donor liver.The total operation time for 7 recipients who successfully underwent laparoscopic-assisted total liver transplantation was(648±31)minutes,with a time of anhepatic phase of(57±5)minutes,the volume of intraoperative blood loss of(1 322±627)mL,the donor liver mass of(1195±232)g,and the ratio of donor liver mass to recipient body mass of 1.86%±0.42%.The operation time for laparoscopic liver dissection and porta hepatis dissection in 8 recipients during surgery was(212±35)minutes.(2)Postoperative conditions.All 9 recipients recovered smoothly after surgery,without any vascular or biliary related complications,and the surgical incision recovered well.The duration of postoperative hospital stay of 7 recipients who successfully underwent laparoscopic-assisted total liver transplantation was(14.2±2.0)days.(3)Follow-up.All 9 recipients were followed up for 3 months after surgery.During the follow-up period,there was no vascular or bile duct related complication.Conclusion Laparoscopic-assisted total liver transplantation can be applied to recipients who meet surgical conditions and achieve good short-term clinical efficacy.