胃食管反流病发生的解剖学基础及手术治疗策略
The anatomical pathogenesis and treatment strategy of gastroesophageal reflux disease
郑铭 1鄂一民 2陆晨 1徐方贵 1刘天宇 1喻春钊1
作者信息
- 1. 南京医科大学附属逸夫医院普通外科,南京 211112
- 2. 南京医科大学第二附属医院普通外科,南京 210011
- 折叠
摘要
胃食管反流病(GERD)是一种常见的消化系统疾病,主要表现为胃、十二指肠内容物反流至食管或者食管外,导致系列临床症状.食管胃连接部是抗反流功能的主要区域,其中食管下端括约肌、膈肌脚、膈食管韧带和His角等解剖结构的异常是GERD发生的重要因素.基于这些解剖结构的重建和修复手术是治疗GERD的有效方法,其丰富的手术方式各有其优势和侧重点.笔者以解剖学视角阐述GERD发生机制与手术方式的合理选择.
Abstract
Gastroesophageal reflux disease(GERD)is a prevalent disorder within the digestive system,characterized by the regurgitation of gastric and duodenal contents into the esophagus or extraesophageal regions,leading to a spectrum of clinical symptoms.The esophagogastric junction serves as the principal area for anti-reflux function,with anomalies in anatomical structures including the lower esophageal sphincter,the crural diaphragm,the phrenoesophageal ligament,and the angle of His as significant factors in the development of GERD.Reconstructive and reparative surgeries based on above anatomical structures are effective methods for treating GERD,with a variety of surgical approaches each offering distinct advantages and focal points.The authors elucidate the anatomical pathogenesis and rational selection of surgical methods for GERD.
关键词
胃食管反流病/食管裂孔疝/发病机制/抗反流手术/解剖学/疗效Key words
Gastroesophageal reflux disease/Hiatal hernia/Pathogenesis/Anti-reflux surgery/Anatomy/Efficacy引用本文复制引用
出版年
2024
NETL
NSTL
万方数据