Esophageal cancer is a common tumor of the upper digestive tract,among which the most common histological subtypes are esophageal squamous cell carcinoma and esophageal adenocarcinoma.Recent advances in microbiological analysis methods have catalyzed a deeper understanding of complex host-microbe interactions and mechanism.Gut microbiome not only act as a role in maintaining host health,but also play a key role in carcinogenesis and therapeutic response prediction.However,studies on the relationship between gut microbiome and tumor focus more on melanoma,colorectal cancer,lung cancer and other cancers,while on esophageal cancer remain undetermined.Therefore,we reviewed the research progress of gut microbiome in esophageal cancer,and the development trend of gut microbiome in early screening,early diagnosis,treatment,monitoring and prevention of tumors were prospected.
关键词
肠道微生物群/食管癌/治疗反应/生物标志物
Key words
Gut microbiome/Esophageal cancer/Therapy response/Biomarker