Mitochondrial ribosomal protein gene sequences from five species,including Homo sa-piens,Mus musculus,Fugu rubripes,Drosophila melanogaster and Caenorhabditis elegans,were used as samples to investigate species differences in the interactions between the first intron and other in-trons.Using the Smith-Waterman method,the optimal matched segments of the reverse complementary sequence between the first intron and other introns of each gene were obtained through local alignment.After standardizing the optimal matched segments dataset of the five species,combined with a new symmetric relative entropy function,the species differences of interactions between the first intron and other introns were analyzed.Research has shown that each species has a conserved peak compared to any other species,indicating that each species has its own unique characteristics,possibly due to the presence of certain special functional elements at these locations.And the optimally matched segments at these positions are key elements that make up special functional components and can reflect differ-ences between species.
关键词
内含子/最佳匹配片段/相对位置分布/相互作用/新对称相对熵
Key words
intron/optimal matched segment/relative position distribution/interaction/new sym-metric relative entropy
维普
万方数据