Effect of electrical stimulation biofeedback on serum serum superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)levels inperimenopausal female patients withpelvic floor dysfunction
Objective To investigate the clinical effect of electrical stimulation biofeedback therapy on post-partum pelvic floor dysfunction and its influence on the levels of serum superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px).Methods 204 patients with postpartum pelvicfloordysfunction(PFD)were selected from pelvic floor center of the hospital between August 2019 to August 2022.102 cases in control group and 102 cases in experimental group were randomly divided into 2 groups.The control group was treated with pelvic floor muscle exercise,and the test group was treated with biofeedback electric stimulation on the basis of the control group.The clinical efficacy,quality of life of pelvic floor muscle strength and changes of serum SOD and GSH-Px levels before and afterthe treatment were compared be-tween the 2 groups.Results After thetreatment,the total effective rate of the test group was 96.08％,and that of the control group was 82.35％.The total effective rate of the test group was higher than that of the control group(X2=4.993,P=0.025).After the treatment,the pelvic floor muscle strength,the maximum value of class Ⅰ and Ⅱmuscle fiberin the test group were significantly better than those in the control group[(4.31±0.80)vs.(3.09±0.76),(31.69±7.62)vs.(23.19±7.17)uv,(44.07±12.89)vs.(34.48±13.15)uv,(t=-7.896,-5.802,-3.719,all P＜0.01)].After the treatment,the levels of serum SOD and GSH-Px in the test group were significantly higher than those in the control group[(5 501.28±512.37)vs.(5 096.31±526.42)μg/mL,(824.33±139.69)vs.(542.68±117.54)pmol/L,(t=-3.937,-11.018,all P＜0.01)].After the treatment,the total score and subscale score of PFDI-20 and the total score and subscale score of PFIQ-7 in the test group were significantly lower than those in the control group(t=1.967～4.840,all P＜0.05).Conclusions Biofeedback electrical stimulation thera-py is helpful to enhance the pelvic floor muscle strength of perimenopausal female PFD patients,increase the serum SOD and GSH-Px levels,and improve the quality of life of the patients.
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