Risk and prediction model of agitation after fiberbronchoscope in children
Objective To investigate the risk of agitation after fiberbronchoscope in children and establish a prediction model.Methods A total of 112 children who underwent fiberbronchoscopy in the hospital from September 2023 to February 2024 were selected as study objects,and the incidence of postoperative agita-tion was analyzed.The children with postoperative agitation were classified into observation group and those without postoperative agitation were classified into control group.The influencing factors of agita-tion after fiberbronchoscope in children were analyzed,and the nomogram prediction model was estab-lished and verified by R3.5.1 software.Results Among the 112 children,34(30.36％)had postoperative agitation,which was assigned to the observation group,and the other 78 cases were assigned to the control group.The 34 patients had 1(41.18％)or 2(47.06％)more agitation after surgery,and the PAED score was mostly 16～18,with 17(35.29％)being the most frequent.The proportion of intravenous anesthesia+inhalation anesthesia,postoperative pain and anesthesiatime in the observation group were higher than those in the control group,and the proportion of age and bifrequency index 50～59 in the observation group were lower than those in the control group(P＜0.05).Age≥6years old,EEG bifrequency index of 50～59 were independent protective factors for agitation after fiberbronchoscope in children.Anesthesia method was intravenous anesthesia+inhalation anesthesia,anesthesia time and postoperative pain were in-dependent risk factors(P＜0.05).Logistic regression equation was established:logit(P)=-4.861-1.163 × age+1.522 × anesthesia method+0.132 × anesthesia time+1.703 × postoperative pain-1.779 × EEG bifrequency index.The C-index of the nomogram model was 0.881,and the area under the ROC curve was 0.881(95％CI:0.806～0.935),the sensitivity was 85.29％,the specificity was 78.21％,and the Yoden index was 0.635.The calibration curve slope results showed that the Brier score was 0.086 and the cali-bration slope was 0.894.Conclusion The risk of agitation after fiberbronchoscope in children is higher,and the influencing factors include age,anesthesia method,anesthesia time,postoperative pain and EEG dual frequency index.The prediction model based on this model has high efficacy.
fiberbronchoscopepostoperative agitationprediction model
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