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观察芬吗通治疗卵巢早衰对卵巢功能的影响

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目的 观察芬吗通在卵巢早衰中的疗效及对患者卵巢功能的影响.方法 以2016年7月-2019年12月期间本院收治的130例卵巢早衰患者为研究对象,随机分为对照组(n=65)及研究组(n=65).对照组患者采用常规激素治疗,研究组患者则采用芬吗通进行治疗.观察并比较2组患者治疗后疗效,检测并比较2组患者治疗前后内分泌激素水平、卵巢功能相关指标.结果 与治疗前相比,治疗后2组患者血清中E2水平显著升高,LH、FSH水平及SSBI评分均显著下降,且治疗后3个月研究组患者E2水平显著高于对照组,LH、FSH水平及SSBI评分均显著低于对照组(P<0.05或P<0.01).与治疗前相比,治疗后3个月2组患者OV、FN、PSV、子宫内膜厚度水平均显著升高,且治疗后3个月时研究组患者上述指标水平均显著高于对照组(P<0.05或P<0.01).结论 芬吗通在卵巢早衰的治疗中不仅可调节患者内分泌激素水平,还能改善患者卵巢功能,提升综合疗效.
Observation about the effect of femostone in premature ovarian failure and its effect on ovarian function
Objective To observe the effect of femostone in premature ovarian failure and its effect on ovarian function.Methods 130 patients with premature ovarian failure admitted to the hospital from July 2016 to December 2019 were selected as the study objects,and were randomized into the control group(n=65)and the study group(n=65).The control group was treated with conventional hormone,the study group was treated with femostone.The efficacy of two groups were observed and compared,and the endocrine hormone level and ovarian function before and after treatment were tested and compared.Results Compared with those before treatment,the E2 levels of two groups increased significantly 3 months after the treatment,the LH、FSH levels and SSBI scores decreased significantly after treatment,and the E2 level of the study group was significantly higher than that in the control group,and the LH,FSH levels and SSBI scores were significantly lower than those in the control group(P<0.05 or P<0.01).Compared with those before treatment,the OV、FN、PSV levels and endometrial thickness of two groups increased significantly 3 months after treatment,and the above index levels were significantly higher than those in the control group at 3 months after treatment(P<0.05 or P<0.01).Conclusion In the treatment of premature ovarian failure,it can not only adjust the endocrine hormone level,but also improve the ovarian function of the patients and improve the comprehensive curative effect.

Early ovarian failureFemostoneEfficacyOvarian function

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唐河县妇幼保健院妇产科,河南唐河 473400

卵巢早衰 芬吗通 疗效 卵巢功能

2024

新疆医学
新疆维吾尔自治区医学会

新疆医学

影响因子:0.385
ISSN:1001-5183
年,卷(期):2024.54(1)
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