Correlative study of blood glucose detection by the application of insulin in growth hormone stimulation test in children with short stature
Objective To investigate the frequency of blood glucose detection by the application of insulin in growth hormone stimulation test in children with short stature to promote the accurate and successful completion of the stimulation test.Methods In 322 children with short stature,using the insulin in growth hormone stimulation test was performed.Before insulin injection and 30 min,60min,90min,and 120min,blood samples were collected to the detection of growth hormone(peripheral blood glucose was measured at 0 min、10 min、15 min、20 min、30 min、60 min、90 min、120 min),the peripheral blood glucoses reach the effective value,that is,when it was lower than 2.8 mmol/l,or half of the basic value.Compared the effectiveness of the peripheral blood glucose of 8 times(measuring peripheral blood glucose 0 min、10 min、15 min、20 min、30 min、60 min、90 min、120 min)with that of 5 times of peripheral blood glucose(measuring peripheral blood glucose 0 min、30 min、60 min、90 min、120 min)to reach the effective blood glucose value.Results 179 cases of peripheral blood glucose reached the effective glucose value within 15 minutes,of which 27 cases exceeded the effective glucose value at 30 minutes;136 cases reached the effective glucose value between 15-30 minutes,of which 19 cases exceeded the effective glucose value at 30 minutes;the effective glucose value was not reached in 17 cases of peripheral blood glucose.8 times of peripheral blood glucose reaching the effective value of blood glucose accounted for 94.72％(305/322),and 5 times of peripheral blood glucose reaching the effective value of blood glucose accounted for 80.4％(259/322),which was a statistically significant difference(P＜0.01).Conclusion Using Insulin in growth hormone stimulation test was an important part of the diagnosis of short stature,and it was the diagnosis condition for diagnosing short stature caused by growth hormone deficiency.Reaching the effective value of blood glucose was a necessary condition for the success of the test,Routine detection of peripheral blood glucose at 0 min、30 min、60 min、90 min、120 min might lead to the loss of effective value of blood glucose,and could strengthen the frequency of detection of peripheral blood glucose,the accuracy of the test would be improved,the failure of some tests would be avoided,and the economy loss would be reduced.
Short statureGrowth hormone stimulation testPeripheral blood glucosesInsulin
NETL
NSTL
万方数据
