Evaluation of effect of clinical pharmacists'intervention in antimicrobial agents in neonatal intensive care unit
Objective To evaluate the intervention effect of clinical pharmacists on the use of antibiotics in neonatal intensive care unit of a grade three hospital.Methods Data of antibiotic use among hospitalized patients in neonatal intensive care unit from July to December 2021(before clinical pharmacist intervention)and from January to June 2022(after clinical pharmacist intervention)were collected through the hospital information system.Statistical analysis was carried out on the intensity of use of antibiotics,combination of drugs,use of antibiotics for unrestricted use,restricted use,special use,utilization rate of prophylactic drugs and course of antibacterial drugs,to evaluate the effect of intervention.Results After intervention,the use intensity of antibacterial,prophylactic drugs,combined drugs,and the use rate of restricted antibiotics decreased compared with before intervention(P<0.05),and the use rate of unrestricted antibiotics increased(P<0.05).The course of antibacterial drugs was shortened compared with that before intervention(P<0.05).Conclusion Clinical pharmacists intervention has obvious effect on the use of antibiotics in neonatal intensive care unit,and more communication and cooperation with physicians can promote the rational use of antibiotics.
Clinical pharmacistNewbornAntibacterial drugsIntensity of antimicrobial use