Application effect of bridging stent therapy in patients with acute cerebral infarction and its influence on neurological function
Objective To study and explore the effect of bridging stents therapy on neurological function in patients with acute ce-rebral infarction.Methods 80 patients with acute cerebral infarction admitted in our hospital from January 2018 to March 2022 were selected and randomly divided into control group(40 cases)and observation group(40 cases)according to the cross double-blind meth-od.The control group was treated with tent thrombectomy,and the observation group received bridging stent thrombectomy.Based on the National Institutes of Health Stroke Scale(NIHSS),the NIHSS scores of the two groups were evaluated and compared before treat-ment and 1 day,10 days,20 days,30 days after treatment.Neuron specific enolase(NSE),ciliary neurotrophic factor(CNTF),brain-derived neurotrophic factor(BDNF)were used to compare the neurological function of the two groups before and after treatment.Based on the modified Rankin scale,the Rankin scores of the two groups were evaluated and compared at day 1,day 10,day 20 and day 30 af-ter treatment.Results There was no difference in NIHSS score between the two groups before treatment and 1 day after treatment(P＞0.05).NIHSS scores in the observation group at 10 days,20 days and 30 days after treatment were lower than those in the control group(P＜0.05).There was no difference in NSE and other neurological functions between the two groups before treatment(P＞0.05).After treatment,NSE and other neurological functions in the observation group were better than those in the control group,and there was a difference between the two groups(P＜0.05).There was no difference in Rankin scores between the two groups on the 1st day after treatment(P＞0.05),and the Rankin scores in the observation group at 10,20 and 30 days after treatment were lower than those in the control group,with differences between the two groups(P＜0.05).Conclusion In order to further improve the clinical ef-fect,the implementation of alteplase intravenous thrombolysis bridging stent thrombectomy in patients with acute cerebral infarction in this study is superior to direct intravascular thrombectomy,which can effectively improve the neurological function and prognosis of pa-tients,and reverse the brain nerve injury at the same time,and it is worthy of promotion.
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